INT93244

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Context Info
Confidence 0.60
First Reported 2001
Last Reported 2006
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.59
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CSAD) small molecule metabolic process (CSAD) lyase activity (CSAD)
cellular nitrogen compound metabolic process (CSAD)
CSAD (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 29 100.00 Very High Very High Very High
Migraine 54 90.00 High High
headache 9 88.36 High High
medulla 1 78.96 Quite High
Sumatriptan 5 75.00 Quite High
imagery 15 48.76 Quite Low
Analgesic 1 25.00 Low Low
glial activation 1 10.32 Low Low
hyperexcitability 6 5.00 Very Low Very Low Very Low
Serotonin 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 29 100.00 Very High Very High Very High
Migraine Without Aura 28 98.22 Very High Very High Very High
Migraine With Aura 27 98.04 Very High Very High Very High
Congenital Anomalies 13 92.00 High High
Headache 51 90.00 High High
Migraine Disorders 7 88.36 High High
Cluster Headache 2 68.88 Quite High
Stroke 2 43.52 Quite Low
Nociception 1 40.68 Quite Low
Epilepsy 19 30.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These studies have focused on CSD-associated NO release at highly acute time points (min-hours) and have not employed markers of NO metabolism with direct clinical application e.g. cGMP.
Neg (NO) Localization (release) of CSD associated with depression
1) Confidence 0.60 Published 2001 Journal Brain Res. Section Abstract Doc Link 11164810 Disease Relevance 0.67 Pain Relevance 0.64
It seems likely that MWA and MWoA are two phenotypes sharing a common pathophysiological substrate, and that asymptomatic CSD may occur in some patients.
Localization (occur) of CSD associated with depression, migraine with aura and migraine without aura
2) Confidence 0.51 Published 2006 Journal PLoS Medicine Section Body Doc Link PMC1609120 Disease Relevance 0.92 Pain Relevance 0.35

General Comments

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