INT93424

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Context Info
Confidence 0.36
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.58
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
skin 1
SLC45A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dismenorea 3 99.74 Very High Very High Very High
Dopamine 9 99.42 Very High Very High Very High
insula 2 95.24 Very High Very High Very High
Nucleus accumbens 9 94.04 High High
Ventral tegmentum 7 92.76 High High
narcan 1 52.32 Quite High
Opioid 2 50.88 Quite High
antagonist 1 50.32 Quite High
melanocortin 1 receptor 1 41.44 Quite Low
agonist 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Alcohol Addiction 1 99.48 Very High Very High Very High
Reprotox - General 1 2 97.72 Very High Very High Very High
Sprains And Strains 2 88.88 High High
Cognitive Disorder 1 81.20 Quite High
Syndrome 4 75.00 Quite High
Attention Deficit Hyperactivity Disorder 2 32.96 Quite Low
Drug Dependence 1 25.00 Low Low
Genetic Predisposition To Disease 1 5.00 Very Low Very Low Very Low
Mental Disorders 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Blum et al. [10] provided the first evidence that the dopamine D2 receptor gene (DRD2) Taq 1 A1 allele significantly associated with severe alcoholism whereby the author's suggested that they found the first "reward gene" located in the mesolimbic system.
1 A1 Binding (associated) of associated with alcohol addiction and dopamine
1) Confidence 0.36 Published 2010 Journal Med. Hypotheses Section Abstract Doc Link 19914781 Disease Relevance 0.33 Pain Relevance 0.66
[Analysis on associations of cytochrome P450 1A1-Hinc II and glutathion S-transferase-theta with primary dysmenorrhea].
1A1 Binding (associations) of associated with dismenorea
2) Confidence 0.35 Published 2001 Journal Zhonghua Yi Xue Yi Chuan Xue Za Zhi Section Title Doc Link 11172643 Disease Relevance 0.10 Pain Relevance 0.29
We found a statistically significant association of MATP-374L (darker skin) with higher TYR protein abundance that was not observed for any NCKX5-111 or OCA2 rs12913832 allele.
MATP-374L Binding (association) of in skin
3) Confidence 0.26 Published 2009 Journal J. Invest. Dermatol. Section Abstract Doc Link 18650849 Disease Relevance 0.15 Pain Relevance 0

General Comments

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