INT93467

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Context Info
Confidence 0.17
First Reported 2001
Last Reported 2006
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.49
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Cldn1) plasma membrane (Cldn1)
Anatomy Link Frequency
ileum 2
Cldn1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 8 99.68 Very High Very High Very High
Pain 2 99.64 Very High Very High Very High
ischemia 28 96.92 Very High Very High Very High
IPN 2 75.00 Quite High
Lasting pain 1 70.88 Quite High
cytokine 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 7 99.68 Very High Very High Very High
Pain 3 99.64 Very High Very High Very High
Reperfusion Injury 21 97.68 Very High Very High Very High
Cv Unclassified Under Development 24 96.92 Very High Very High Very High
Inflammatory Pain 2 75.00 Quite High
Injury 1 57.44 Quite High
Necrosis 1 39.52 Quite Low
Cv General 4 Under Development 4 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 2 5.00 Very Low Very Low Very Low
Enteropathy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Claudin-1 protein expression was present at the BBB and remained unchanged during inflammation.
Neg (unchanged) Positive_regulation (unchanged) of Gene_expression (expression) of Claudin-1 protein associated with inflammation
1) Confidence 0.17 Published 2001 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 11179069 Disease Relevance 0.91 Pain Relevance 0.69
Immunohistochemistry using control sections of rat ileum demonstrated the expression of claudin-1, claudin-2, claudin-3, claudin-4, claudin-5, ZO-1, and occludin.
Positive_regulation (demonstrated) of Gene_expression (expression) of claudin-1 in ileum
2) Confidence 0.17 Published 2006 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC1828083 Disease Relevance 0.58 Pain Relevance 0.13

General Comments

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