INT9350

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Context Info
Confidence 0.12
First Reported 1990
Last Reported 2008
Negated 0
Speculated 1
Reported most in Abstract
Documents 9
Total Number 10
Disease Relevance 1.53
Pain Relevance 7.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ADORA1) endoplasmic reticulum (ADORA1) plasma membrane (ADORA1)
cell-cell signaling (ADORA1) signal transducer activity (ADORA1)
ADORA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
adenocard 316 100.00 Very High Very High Very High
narcan 7 100.00 Very High Very High Very High
agonist 262 99.96 Very High Very High Very High
antagonist 95 99.96 Very High Very High Very High
Analgesic 8 99.92 Very High Very High Very High
Morphine 27 98.84 Very High Very High Very High
Serotonin 4 98.36 Very High Very High Very High
analgesia 3 97.28 Very High Very High Very High
IPN 1 93.56 High High
sSRI 2 86.60 High High
Disease Link Frequency Relevance Heat
Nociception 1 99.48 Very High Very High Very High
Catalepsy 6 98.16 Very High Very High Very High
Inflammatory Pain 1 93.56 High High
Diabetes Mellitus 7 90.24 High High
INFLAMMATION 30 83.28 Quite High
Disease 13 77.68 Quite High
Necrosis 4 67.52 Quite High
Cancer 24 67.16 Quite High
Wound Healing 2 65.28 Quite High
Sleep Disorders 6 62.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We used this rodent cell line because of further experiments concerning the influence of adenosine receptor antagonists on insulin secretion in vitro and in vivo.
Regulation (influence) of adenosine receptor associated with adenocard and antagonist
1) Confidence 0.12 Published 2006 Journal Purinergic Signal Section Body Doc Link PMC2096648 Disease Relevance 0.09 Pain Relevance 0.52
Effects of adenosine receptor agonists and antagonists on morphine-induced catalepsy in mice were investigated.
Regulation (Effects) of adenosine receptor associated with adenocard, catalepsy, antagonist, agonist and morphine
2) Confidence 0.08 Published 1997 Journal Eur. J. Pharmacol. Section Abstract Doc Link 9407998 Disease Relevance 0.22 Pain Relevance 0.93
Effect of adenosine receptor agonists and antagonists on morphine-induced catalepsy in mice.
Regulation (Effect) of adenosine receptor associated with adenocard, catalepsy, antagonist, narcan, agonist and morphine
3) Confidence 0.08 Published 1997 Journal Eur. J. Pharmacol. Section Title Doc Link 9407998 Disease Relevance 0.26 Pain Relevance 1.53
The effect of adenosine receptor agonists on analgesic effects of morphine.
Regulation (effect) of adenosine receptor associated with adenocard, analgesic, agonist and morphine
4) Confidence 0.03 Published 1990 Journal Pol J Pharmacol Pharm Section Title Doc Link 2281016 Disease Relevance 0 Pain Relevance 1.46
The effect of selective adenosine receptor agonists on nociceptive responses of mice and rats and on morphine analgesia was investigated.
Spec (investigated) Regulation (effect) of adenosine receptor associated with nociception, adenocard, agonist, analgesia and morphine
5) Confidence 0.01 Published 1992 Journal Pol J Pharmacol Pharm Section Abstract Doc Link 1409113 Disease Relevance 0.10 Pain Relevance 0.73
Upon agonist treatment, adenosine receptor subtypes are differently regulated.
Regulation (regulated) of adenosine receptor associated with adenocard and agonist
6) Confidence 0.01 Published 2007 Journal Purinergic Signal Section Abstract Doc Link PMC2245999 Disease Relevance 0.08 Pain Relevance 0.31
The adenosine receptor subtypes are differentially regulated when exposed to agonist treatment.
Regulation (regulated) of adenosine receptor associated with adenocard and agonist
7) Confidence 0.01 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2245999 Disease Relevance 0.20 Pain Relevance 0.25
To clarify the effects of adenosine receptor subtypes (A1, A2 and A3) on hippocampal serotonin (5-HT) release and 5-HT reuptake activity, hippocampal extracellular 5-HT levels were determined in vivo by microdialysis in freely moving rats.
Regulation (effects) of adenosine receptor associated with adenocard and serotonin
8) Confidence 0.01 Published 1999 Journal Eur. J. Neurosci. Section Abstract Doc Link 9987006 Disease Relevance 0 Pain Relevance 0.58
Differential effects of adenosine receptor subtypes on release and reuptake of hippocampal serotonin.
Regulation (effects) of adenosine receptor associated with adenocard and serotonin
9) Confidence 0.01 Published 1999 Journal Eur. J. Neurosci. Section Title Doc Link 9987006 Disease Relevance 0.12 Pain Relevance 0.99
The adenosine receptor, Adora2b was also strongly induced by LPS in BMM (191-fold at 6 h) yet was only modestly regulated (3-fold at 7 h) in TEPM.
Regulation (regulated) of adenosine receptor associated with adenocard
10) Confidence 0.00 Published 2008 Journal Immunome Res Section Body Doc Link PMC2394514 Disease Relevance 0.46 Pain Relevance 0.49

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