INT93577

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Context Info
Confidence 0.46
First Reported 2000
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.75
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Dysf)
Dysf (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 5 99.20 Very High Very High Very High
Inflammation 4 92.92 High High
COX-2 inhibitor 1 91.32 High High
Inflammatory stimuli 1 84.80 Quite High
cINOD 1 76.12 Quite High
Pain 1 65.00 Quite High
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 5 92.92 High High
Frailty 4 84.68 Quite High
Pleurisy 1 80.08 Quite High
Fever 1 65.40 Quite High
Pain 1 65.00 Quite High
Muscle Disease 3 55.68 Quite High
Distal Myopathy 1 52.56 Quite High
Disease 6 5.00 Very Low Very Low Very Low
Sarcoglycanopathies 3 5.00 Very Low Very Low Very Low
Hypertrophy 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
LGMD type2B (LGMD2B) is caused by mutations in the dysferline gene (DYSF, MIM*603009) located on chromosome 2p13.3, which induces a dysfunction of dysferlin at the protein level (2).
Positive_regulation (dysfunction) of dysferlin
1) Confidence 0.46 Published 2004 Journal Journal of Korean Medical Science Section Body Doc Link PMC2816849 Disease Relevance 0.19 Pain Relevance 0
Thus, evidence is accumulating for the existence of a COX-2 variant or a new COX enzyme which can be inhibited with paracetamol.
Positive_regulation (accumulating) of variant associated with paracetamol
2) Confidence 0.01 Published 2000 Journal J. Physiol. Pharmacol. Section Abstract Doc Link 11192935 Disease Relevance 0.56 Pain Relevance 0.77

General Comments

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