INT93618

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Context Info
Confidence 0.16
First Reported 2000
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 2.31
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (TREH) hydrolase activity, acting on glycosyl bonds (TREH) plasma membrane (TREH)
carbohydrate metabolic process (TREH)
Anatomy Link Frequency
upper limb 1
TREH (Homo sapiens)
Pain Link Frequency Relevance Heat
Nav1.7 3 99.84 Very High Very High Very High
Transcranial magnetic stimulation 4 92.08 High High
Pain 2 88.16 High High
nud 1 86.80 High High
sodium channel 2 79.24 Quite High
withdrawal 1 78.40 Quite High
dorsal root ganglion 24 5.00 Very Low Very Low Very Low
ischemia 10 5.00 Very Low Very Low Very Low
cva 8 5.00 Very Low Very Low Very Low
nociceptor 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 47 100.00 Very High Very High Very High
Reprotox - General 1 9 98.88 Very High Very High Very High
Giardiasis 7 96.44 Very High Very High Very High
Disease 9 94.48 High High
Pain 1 88.16 High High
Metastasis 1 88.12 High High
Dyspepsia 1 86.80 High High
Pre-term Labor 6 73.84 Quite High
Targeted Disruption 4 66.44 Quite High
Coronary Heart Disease 11 65.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Estimation of lactase, sucrase, maltase and trehalase was done in biopsies.
Positive_regulation (Estimation) of trehalase
1) Confidence 0.16 Published 2000 Journal Trop Gastroenterol Section Abstract Doc Link 11194577 Disease Relevance 0.76 Pain Relevance 0.13
We conclude that activation of A-alpha and A-delta fibers gives rise to complex modulatory effects on upper limb motoneuron pools.
Positive_regulation (activation) of A-alpha in upper limb
2) Confidence 0.06 Published 2001 Journal Clin Neurophysiol Section Abstract Doc Link 11377265 Disease Relevance 0 Pain Relevance 0.26
Tertiary hospitals and interventional cardiologists are understandably eager to extend these services to community and regional hospitals, since, beyond the conviction that this is the best approach, this also reinforces their raison d'ĂȘtre, justifying claims for more new high-tech resources and, depending on the socioeconomic environment, potentially increasing revenues.
Positive_regulation (increasing) of raison d' tre
3) Confidence 0.05 Published 2006 Journal BMC Med Section Body Doc Link PMC1617111 Disease Relevance 0.25 Pain Relevance 0
Importantly, RT-PCRs identified Nav1.7 as the VGSCalpha most strikingly upregulated (approximately 20-fold) in CaP, and the resultant receiver-operating characteristics curve demonstrated high diagnostic efficacy for the disease.
Positive_regulation (upregulated) of VGSCalpha associated with disease, nav1.7 and reprotox - general 1
4) Confidence 0.03 Published 2005 Journal Prostate Cancer Prostatic Dis. Section Abstract Doc Link 16088330 Disease Relevance 0.81 Pain Relevance 0.34
The expression of Runx1 in DOX-treated and control neurospheres was monitored by the concomitant induction of EYFP expression from the bidirectional TRE promoter (Fig. 1E, 1F).
Positive_regulation (induction) of TRE
5) Confidence 0.01 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2733376 Disease Relevance 0.07 Pain Relevance 0
By using phosphotyrosine screening and mass spectrometry of stretched human myometrial samples, we identify 3 stretch-activated focal adhesion proteins, FAK, p130Cas, and alpha actinin.
Positive_regulation (activated) of alpha associated with adhesions
6) Confidence 0.00 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2759504 Disease Relevance 0.43 Pain Relevance 0

General Comments

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