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Context Info
Confidence 0.04
First Reported 2001
Last Reported 2008
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 1.88
Pain Relevance 1.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (PTGES2) cytosol (PTGES2) mitochondrion (PTGES2)
Golgi apparatus (PTGES2) nucleus (PTGES2) DNA binding (PTGES2)
Anatomy Link Frequency
nerve 1
PGE2 1
PTGES2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 7 100.00 Very High Very High Very High
Nerve growth factor 5 100.00 Very High Very High Very High
substance P 2 99.76 Very High Very High Very High
Inflammation 5 94.04 High High
Pain 1 86.04 High High
Analgesic 3 85.64 High High
anesthesia 1 80.92 Quite High
Pain score 1 78.48 Quite High
cINOD 3 71.36 Quite High
Inflammatory mediators 2 39.16 Quite Low
Disease Link Frequency Relevance Heat
Neuroblastoma 1 99.38 Very High Very High Very High
Injury 11 98.72 Very High Very High Very High
INFLAMMATION 8 94.04 High High
Nociception 3 93.36 High High
Alzheimer's Dementia 1 89.32 High High
Disease 8 86.16 High High
Pain 2 86.04 High High
Urological Neuroanatomy 1 80.00 Quite High
Cancer 1 68.60 Quite High
Necrosis 1 68.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vitro, primary human microglial and astrocyte cultures, and human neuroblastoma cells (SK-N-SH) were found to secrete prostaglandin E2 (PGE2), especially when stimulated.
Localization (secrete) of prostaglandin E2 in PGE2 associated with neuroblastoma
1) Confidence 0.04 Published 2001 Journal Acta Neuropathol. Section Abstract Doc Link 11194936 Disease Relevance 0.93 Pain Relevance 0.24
Local and systemic release of cytokines, nerve growth factor, prostaglandin E2, and substance P in incisional wounds and serum following cesarean delivery.
Localization (release) of prostaglandin E2 in nerve associated with nerve growth factor, injury, substance p and cytokine
2) Confidence 0.00 Published 2008 Journal J Pain Section Title Doc Link 18394968 Disease Relevance 0.95 Pain Relevance 0.93

General Comments

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