INT93674

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Context Info
Confidence 0.38
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Creb1) mitochondrion (Creb1) nucleolus (Creb1)
nucleus (Creb1) DNA binding (Creb1) transcription factor binding (Creb1)
Creb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Opioid 6 99.98 Very High Very High Very High
addiction 2 96.32 Very High Very High Very High
Morphine 2 72.32 Quite High
cocaine 1 68.40 Quite High
opiate 1 44.96 Quite Low
Disease Link Frequency Relevance Heat
Drug Dependence 1 96.52 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Opioids regulate CREB level, its phosphorylation and binding to its corresponding response element in the promoters of several genes implicated in drug addiction.
Regulation (regulate) of CREB Binding (binding) of associated with drug dependence, addiction and opioid
1) Confidence 0.38 Published 2000 Journal Acta Neurobiol Exp (Wars) Section Abstract Doc Link 11200184 Disease Relevance 0.10 Pain Relevance 0.62

General Comments

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