INT9386

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.72
First Reported 1990
Last Reported 2009
Negated 1
Speculated 0
Reported most in Title
Documents 7
Total Number 7
Disease Relevance 0.53
Pain Relevance 2.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Cpe) extracellular space (Cpe) Golgi apparatus (Cpe)
Anatomy Link Frequency
brain 3
BRL-3A 1
adrenal medulla 1
band 1
Cpe (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 20 100.00 Very High Very High Very High
medulla 6 98.08 Very High Very High Very High
Neurotransmitter 8 93.60 High High
Pain 1 91.24 High High
Dynorphin 6 90.64 High High
Neuropeptide 6 75.00 Quite High
Pyramidal cell 4 61.76 Quite High
Hippocampus 4 60.84 Quite High
amygdala 2 54.92 Quite High
Kinase C 15 54.64 Quite High
Disease Link Frequency Relevance Heat
Stress 7 99.76 Very High Very High Very High
Insulin Coma 2 95.20 Very High Very High Very High
Pain 1 91.24 High High
Gliosis 2 30.52 Quite Low
Disease 3 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
Drug Dependence 2 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Neurological Disease 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Carboxypeptidase E (enkephalin convertase): mRNA distribution in rat brain by in situ hybridization.
Transcription (distribution) of Carboxypeptidase E in brain associated with enkephalin
1) Confidence 0.72 Published 1990 Journal J. Neurosci. Section Title Doc Link 2388090 Disease Relevance 0 Pain Relevance 0.36
Carboxypeptidase E (enkephalin convertase): mRNA distribution in rat brain by in situ hybridization.
Transcription (distribution) of enkephalin convertase in brain associated with enkephalin
2) Confidence 0.72 Published 1990 Journal J. Neurosci. Section Title Doc Link 2388090 Disease Relevance 0 Pain Relevance 0.36
[Effect of stress factors on carboxypeptidase H activity in areas of the rat brain].
Transcription (activity) of carboxypeptidase H in brain associated with stress
3) Confidence 0.69 Published 1992 Journal Ukr. Biokhim. Zh. Section Title Doc Link 1413117 Disease Relevance 0.38 Pain Relevance 0.09
Reflex splanchnic nerve stimulation increases levels of carboxypeptidase E mRNA and enzymatic activity in the rat adrenal medulla.
Transcription (levels) of carboxypeptidase E in adrenal medulla associated with medulla and enkephalin
4) Confidence 0.53 Published 1990 Journal J. Neurochem. Section Title Doc Link 2370548 Disease Relevance 0.06 Pain Relevance 0.60
The time course of the change in CPE mRNA levels is similar to that previously found for proenkephalin mRNA.
Transcription (levels) of CPE
5) Confidence 0.53 Published 1990 Journal J. Neurochem. Section Abstract Doc Link 2370548 Disease Relevance 0.10 Pain Relevance 0.51
As showed in Fig. 3D, in the absence of CPE, the DAT-positive band was prominent at 6 hours but began to disappear at 12 hours and was completely absent at 24 hours.
Neg (absence) Transcription (absence) of CPE in band
6) Confidence 0.42 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0.05
Northern blot analysis indicates that BRL-3A cells express carboxypeptidase E mRNA in addition to mRNA encoding furin, a prohormone-processing endopeptidase.
Transcription (express) of carboxypeptidase E in BRL-3A
7) Confidence 0.31 Published 1993 Journal Mol. Cell. Endocrinol. Section Abstract Doc Link 8375574 Disease Relevance 0 Pain Relevance 0.33

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox