INT93916

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Context Info
Confidence 0.25
First Reported 2001
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 5.58
Pain Relevance 1.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (IFNAR1)
Anatomy Link Frequency
satellite cells 1
nerve 1
sympathetic 1
IFNAR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory marker 2 91.80 High High
Pain 13 91.20 High High
headache 1 90.48 High High
rheumatoid arthritis 56 88.92 High High
Rsd 5 75.00 Quite High
reflex sympathetic dystrophy 5 75.00 Quite High
ketamine 2 50.00 Quite Low
Analgesic 1 50.00 Quite Low
Osteoarthritis 1 46.56 Quite Low
allodynia 2 29.84 Quite Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 43 100.00 Very High Very High Very High
Complex Regional Pain Syndromes 31 100.00 Very High Very High Very High
Chronic Hepatitis 3 99.40 Very High Very High Very High
Infection 7 99.34 Very High Very High Very High
Dengue 2 98.88 Very High Very High Very High
Nervous System Injury 5 98.80 Very High Very High Very High
Disease 15 95.24 Very High Very High Very High
Injury 4 93.32 High High
Fever 1 93.12 High High
INFLAMMATION 11 91.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion, it is suggested that, in CRPS I, unilateral inhibition of sympathetic vasoconstrictor neurones leads to a warmer affected limb in the acute stage.
Positive_regulation (leads) of CRPS I in sympathetic associated with complex regional pain syndromes
1) Confidence 0.25 Published 2001 Journal Brain Section Abstract Doc Link 11222458 Disease Relevance 0.74 Pain Relevance 0.15
Efficient dengue virus (DENV) infection of human muscle satellite cells upregulates type I interferon response genes and differentially modulates MHC I expression on bystander and DENV-infected cells.
Positive_regulation (upregulates) of type I interferon in satellite cells associated with dengue and infection
2) Confidence 0.16 Published 2008 Journal J. Gen. Virol. Section Title Doc Link 18559930 Disease Relevance 1.42 Pain Relevance 0.18
We tested the hypotheses that CRPS-I is caused by persistent minimal distal nerve injury (MDNI), specifically distal degeneration of small-diameter axons.
Positive_regulation (caused) of CRPS-I in nerve associated with complex regional pain syndromes and nervous system injury
3) Confidence 0.08 Published 2006 Journal Pain Section Abstract Doc Link 16427737 Disease Relevance 1.24 Pain Relevance 0.38
Maternally inherited mitochondrial disease may not be a rare cause of CRPS-I, especially in children who present with other manifestations of dysautonomia.


Positive_regulation (cause) of CRPS-I
4) Confidence 0.03 Published 2008 Journal Arch. Dis. Child. Section Body Doc Link 18192313 Disease Relevance 0 Pain Relevance 0
A 59-year-old Caucasian suffering from chronic hepatitis C started daily subcutaneous self-injections of interferon alfacon-1 (consensus interferon) according to the protocol of a randomised multicentre study.
Positive_regulation (self-injections) of interferon alfacon-1 associated with chronic hepatitis
5) Confidence 0.02 Published 2005 Journal Eur. J. Med. Res. Section Abstract Doc Link 15817424 Disease Relevance 0.66 Pain Relevance 0.09
In addition, one year of therapy with DMARDs resulted in a significant increase in the serum levels of total cholesterol, HDL-cholesterol and Apo A-I compared with the respective baseline values (Table 1).
Positive_regulation (increase) of A-I associated with disorder of lipid metabolism
6) Confidence 0.01 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1860077 Disease Relevance 1.37 Pain Relevance 0.29
No apparent changes were noticed in 1 patient with chronic atrophic stage of CRPS I and in both patients with CRPS II.
Positive_regulation (stage) of CRPS I
7) Confidence 0.01 Published 2002 Journal Reg Anesth Pain Med Section Body Doc Link 12373705 Disease Relevance 0.08 Pain Relevance 0

General Comments

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