INT94031

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Context Info
Confidence 0.24
First Reported 2001
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 3.36
Pain Relevance 3.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Dbi) transport (Dbi) mitochondrion (Dbi)
extracellular space (Dbi) plasma membrane (Dbi) nucleus (Dbi)
Dbi (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 34 99.64 Very High Very High Very High
opioid receptor 4 97.00 Very High Very High Very High
withdrawal 18 96.84 Very High Very High Very High
antagonist 4 95.04 Very High Very High Very High
Morphine 8 92.72 High High
Nicotine 8 92.16 High High
alcohol 4 86.44 High High
Neuropeptide 2 75.92 Quite High
agonist 2 75.52 Quite High
Disease Link Frequency Relevance Heat
Drug Dependence 34 99.84 Very High Very High Very High
Opiate Addiction 16 96.84 Very High Very High Very High
Anxiety Disorder 5 82.84 Quite High
Substance Withdrawal Syndrome 2 81.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, these alterations in DBI expression have a close relationship with formation of drug dependence and/or emergence of withdrawal syndrome and are considered to be a common biochemical process in drug dependence induced by different drugs of abuse.
Regulation (alterations) of Gene_expression (expression) of DBI associated with drug dependence, addiction and withdrawal
1) Confidence 0.24 Published 2001 Journal Nippon Yakurigaku Zasshi Section Abstract Doc Link 11288485 Disease Relevance 0.84 Pain Relevance 0.84
Alterations in cerebral diazepam binding inhibitor expression in drug dependence: a possible biochemical alteration common to drug dependence.
Regulation (Alterations) of Gene_expression (expression) of diazepam binding inhibitor associated with drug dependence and addiction
2) Confidence 0.24 Published 2001 Journal Life Sci. Section Title Doc Link 11233989 Disease Relevance 0.89 Pain Relevance 0.64
Therefore, these alterations in DBI expression have close relationship with formation of drug dependence and/or emergence of withdrawal syndrome, and are considered to be a common biochemical process in drug dependence induced by different drugs of abuse.
Regulation (alterations) of Gene_expression (expression) of DBI associated with drug dependence, addiction and withdrawal
3) Confidence 0.24 Published 2001 Journal Life Sci. Section Abstract Doc Link 11233989 Disease Relevance 0.92 Pain Relevance 0.96
Therefore, these alterations in DBI expression, mediated via increased influx of Ca2+ through upregulated L-type HVCCs, are closely related to drug dependence and/or its withdrawal syndrome and are considered to be part of a common biochemical process in drug dependence induced by different drugs of abuse.
Regulation (alterations) of Gene_expression (expression) of DBI associated with drug dependence, addiction and withdrawal
4) Confidence 0.24 Published 2004 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 15542765 Disease Relevance 0.70 Pain Relevance 0.65

General Comments

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