INT94075

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Context Info
Confidence 0.28
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.26
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL4) extracellular region (IL4) small molecule metabolic process (ARSA)
plasma membrane (ARSA) lysosome (ARSA)
Anatomy Link Frequency
T cells 4
ARSA (Homo sapiens)
IL4 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 4 97.68 Very High Very High Very High
cINOD 2 96.60 Very High Very High Very High
aspirin 8 83.32 Quite High
Inflammation 2 68.48 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 4 96.48 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ASA inhibited IL-4, but not IL-2, promoter-driven chloramphenicol acetyltransferase expression in transiently transfected Jurkat T cells.
ASA Negative_regulation (inhibited) of Gene_expression (expression) of IL-4 in T cells
1) Confidence 0.28 Published 2001 Journal Blood Section Abstract Doc Link 11238116 Disease Relevance 0.09 Pain Relevance 0.30
The structurally unrelated nonsteroidal anti-inflammatory drugs indomethacin and flurbiprofen did not affect cytokine gene expression in T cells, whereas the weak cyclo-oxygenase inhibitor salicylic acid was at least as effective as ASA in inhibiting IL-4 expression and promoter activity.
ASA Negative_regulation (inhibiting) of Gene_expression (expression) of IL-4 in T cells associated with inflammation, cinod and cytokine
2) Confidence 0.18 Published 2001 Journal Blood Section Abstract Doc Link 11238116 Disease Relevance 0.16 Pain Relevance 0.32

General Comments

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