INT94081

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Context Info
Confidence 0.38
First Reported 2001
Last Reported 2003
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.43
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL4) extracellular region (IL4)
Anatomy Link Frequency
T cells 2
IL4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 7 88.80 High High
cytokine 10 85.84 High High
rheumatoid arthritis 54 84.76 Quite High
cINOD 2 83.68 Quite High
aspirin 4 75.00 Quite High
Inflammatory response 3 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 13 88.80 High High
Rheumatoid Arthritis 54 84.76 Quite High
Disease 6 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The inhibitory effect of ASA on IL-4 transcription was not mediated by decreased nuclear expression of the known salicylate target nuclear factor (NF)-kappaB and was accompanied by reduced binding of an inducible factor to an IL-4 promoter region upstream of, but not overlapping, the NF of activated T cells- and NF-kappaB-binding P1 element.
Neg (not) Negative_regulation (reduced) of IL-4 Neg (not) Binding (binding) of in T cells
1) Confidence 0.38 Published 2001 Journal Blood Section Abstract Doc Link 11238116 Disease Relevance 0.17 Pain Relevance 0.30
The combination of IL-7 and IL-4 reduced IFN-?
Negative_regulation (reduced) of IL-4 Binding (combination) of
2) Confidence 0.34 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC193727 Disease Relevance 0.26 Pain Relevance 0.13

General Comments

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