INT94084

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Context Info
Confidence 0.22
First Reported 2001
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 3.55
Pain Relevance 1.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL13) extracellular space (IL13) extracellular region (IL13)
cell-cell signaling (IL13) cytoplasm (IL13)
Anatomy Link Frequency
mast cells 2
IL13 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 210 100.00 Very High Very High Very High
Inflammation 51 90.60 High High
chemokine 21 88.32 High High
cINOD 3 86.64 High High
dexamethasone 8 85.88 High High
aspirin 4 85.44 High High
antagonist 24 60.32 Quite High
tolerance 2 60.00 Quite High
corticosteroid 10 50.72 Quite High
agonist 7 37.80 Quite Low
Disease Link Frequency Relevance Heat
Respiratory Syncytial Virus 57 99.84 Very High Very High Very High
Common Cold 85 99.04 Very High Very High Very High
Asthma 75 97.32 Very High Very High Very High
Infection 43 96.64 Very High Very High Very High
INFLAMMATION 57 90.60 High High
Respiratory Disease 3 82.88 Quite High
Hypersensitivity 35 82.04 Quite High
Disease 48 81.60 Quite High
Convalescence 9 79.52 Quite High
Stress 26 55.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, ASA did not affect IL-13, interferon-gamma, and IL-2 expression.
Neg (not) Regulation (affect) of Gene_expression (expression) of IL-13
1) Confidence 0.22 Published 2001 Journal Blood Section Abstract Doc Link 11238116 Disease Relevance 0.09 Pain Relevance 0.29
These events ultimately lead to the release of important cytokines such as IL-4 and IL-13 critical for immunoglobulin E (IgE) production.
Regulation (critical) of Gene_expression (production) of IL-13 associated with cytokine
2) Confidence 0.19 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2946700 Disease Relevance 0.69 Pain Relevance 0.29
and later by epinephrine, may explain the enhancing effect on the production of IL-6, IL-8, and IL-13 in mast cells.
Regulation (effect) of Gene_expression (production) of IL-13 in mast cells
3) Confidence 0.10 Published 2004 Journal BMC Immunol Section Body Doc Link PMC521685 Disease Relevance 0.27 Pain Relevance 0.18
Dex also significantly inhibited the enhancing effect of epinephrine on IL-8 and IL-13 production (p < 0.05, Fig. 6B and 6C).
Regulation (effect) of Gene_expression (production) of IL-13
4) Confidence 0.10 Published 2004 Journal BMC Immunol Section Body Doc Link PMC521685 Disease Relevance 0.16 Pain Relevance 0.42
In agreement, the RV affected children had markedly higher systemic levels of IL-5 and IL-13 than those affected by RSV in our study, but this difference appeared to be linked to atopy.
Regulation (affected) of Gene_expression (levels) of IL-13 associated with asthma, common cold and respiratory syncytial virus
5) Confidence 0.05 Published 2009 Journal Respir Res Section Body Doc Link PMC2762974 Disease Relevance 2.12 Pain Relevance 0.37
The levels of other cytokines such as IL-2, IL-4, IL-12, IL-13, IL-17, IFN-?
Regulation (levels) of Gene_expression (cytokines) of IL-13 associated with cytokine
6) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2625438 Disease Relevance 0.23 Pain Relevance 0.35

General Comments

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