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Context Info
Confidence 0.49
First Reported 2001
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.93
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (CDK1) mitochondrion (CDK1) protein complex assembly (CDK1)
cytoplasm (CDK1) cytosol (CDK1) mitosis (CDK1)
CDK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 6 53.04 Quite High
Kinase C inhibitor 1 31.12 Quite Low
headache 1 25.00 Low Low
Kinase C 3 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Retinoblastoma 4 100.00 Very High Very High Very High
Hematologic Neoplasms 4 95.64 Very High Very High Very High
Apoptosis 6 80.08 Quite High
Lymphatic System Cancer 2 61.76 Quite High
Stomach Cancer 1 58.80 Quite High
Diarrhoea 1 55.36 Quite High
INFLAMMATION 7 53.04 Quite High
Syndrome 1 52.00 Quite High
Aneuploidy 22 50.00 Quite Low
Pressure Volume 2 Under Development 1 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Loss in Rb function is, in most cases, a result of the phosphorylation and inactivation of Rb by the cyclin-dependent kinases (cdks), main regulators of cell cycle progression.
Positive_regulation (inactivation) of Phosphorylation (phosphorylation) of cdk associated with retinoblastoma
1) Confidence 0.49 Published 2001 Journal Leukemia Section Abstract Doc Link 11243375 Disease Relevance 0.93 Pain Relevance 0.03
treatment of HEK cells stably expressing the human FP prostanoid receptor increases expression of cyclin B1 (A) and increases Cdc2-mediated phosphorylation of histone H1 (B).
Positive_regulation (increases) of Phosphorylation (phosphorylation) of Cdc2
2) Confidence 0.24 Published 2005 Journal Cell Mol Life Sci Section Body Doc Link PMC2792351 Disease Relevance 0 Pain Relevance 0

General Comments

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