INT94176

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Context Info
Confidence 0.11
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.09
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (NEU1) hydrolase activity, acting on glycosyl bonds (NEU1) cytoplasmic membrane-bounded vesicle (NEU1)
plasma membrane (NEU1) lysosome (NEU1)
Anatomy Link Frequency
brain 1
NEU1 (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 1 73.40 Quite High
Central nervous system 1 67.44 Quite High
Disease Link Frequency Relevance Heat
Mucopolysaccharidoses 9 97.76 Very High Very High Very High
Lysosome Storage Disease 3 75.00 Quite High
Gangliosidoses 1 63.24 Quite High
Intellectual Impairment 1 59.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These changes may be, in part, due to the reduction of sialidase and UDP-N-acetylgalactosamine:GM3 N-acetylgalactosaminyltransferase (GalNAc-T) activities in MPS IIID caprine brain.
Negative_regulation (reduction) of sialidase in brain associated with mucopolysaccharidoses
1) Confidence 0.11 Published 2001 Journal Mol. Genet. Metab. Section Abstract Doc Link 11243730 Disease Relevance 1.09 Pain Relevance 0.11

General Comments

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