INT94233

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.69
First Reported 2001
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.64
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Clu) endoplasmic reticulum (Clu) response to stress (Clu)
cytoplasm (Clu) cytosol (Clu) extracellular space (Clu)
Anatomy Link Frequency
pancreas 2
Clu (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 2 99.48 Very High Very High Very High
Chronic pancreatitis 3 98.68 Very High Very High Very High
Inflammatory response 4 95.12 Very High Very High Very High
Kinase C 42 89.36 High High
TRP channel 10 33.08 Quite Low
qutenza 88 22.56 Low Low
dorsal root ganglion 56 20.96 Low Low
antagonist 4 13.56 Low Low
imagery 18 5.00 Very Low Very Low Very Low
Inflammation 11 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 2 99.48 Very High Very High Very High
Ocular Hypertension 1 98.76 Very High Very High Very High
Pancreatitis 3 98.68 Very High Very High Very High
Injury 34 97.28 Very High Very High Very High
Apoptosis 32 95.96 Very High Very High Very High
INFLAMMATION 15 95.12 Very High Very High Very High
Necrosis 6 90.20 High High
Cancer 6 89.84 High High
Optic Nerve Injuries 34 89.00 High High
Retina Disease 4 80.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results show that clusterin is overexpressed in the pancreas at the onset of chronic pancreatitis in vivo and in cultured acinar cells in response to various stimuli in vitro, suggesting that clusterin is a defense mechanism of the exocrine pancreas.
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of clusterin in pancreas associated with chronic pancreatitis
1) Confidence 0.69 Published 2001 Journal Pancreas Section Abstract Doc Link 11249066 Disease Relevance 0.64 Pain Relevance 0.25
An increase of Clusterin and Lipocalin 2 expression together with that of ceruloplasmin and early growth response 1 (Egr1) is associated with increased apoptosis and immune-inflammatory responses [41,42].
Positive_regulation (increase) of Gene_expression (expression) of Clusterin associated with inflammatory response and apoptosis
2) Confidence 0.23 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2426719 Disease Relevance 1.86 Pain Relevance 0.14
Endogenously produced DAG activates TRPV1 channels in a heterologous expression system
Positive_regulation (Endogenously) of Gene_expression (produced) of DAG
3) Confidence 0.18 Published 2008 Journal Mol Pain Section Body Doc Link PMC2576176 Disease Relevance 0.07 Pain Relevance 0.18
DAG is produced upon activation of G?
Positive_regulation (activation) of Gene_expression (produced) of DAG
4) Confidence 0.15 Published 2008 Journal Mol Pain Section Body Doc Link PMC2576176 Disease Relevance 0.07 Pain Relevance 0.15

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox