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Context Info
Confidence 0.38
First Reported 2000
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.52
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

generation of precursor metabolites and energy (ADRB3) aging (ADRB3) plasma membrane (ADRB3)
nucleus (ADRB3) carbohydrate metabolic process (ADRB3) signal transducer activity (ADRB3)
ADRB3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Clonidine 1 94.72 High High
Dopamine 1 93.36 High High
cytokine 5 90.24 High High
anesthesia 3 84.88 Quite High
epidural 2 84.44 Quite High
Angina 1 32.04 Quite Low
Inflammation 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Aging 3 99.98 Very High Very High Very High
Pressure Volume 2 Under Development 1 96.64 Very High Very High Very High
Necrosis 2 75.00 Quite High
Cancer 2 75.00 Quite High
Pyloric Stenosis 1 72.08 Quite High
Heart Disease 2 35.16 Quite Low
Myocardial Infarction 2 33.32 Quite Low
Cv General 3 Under Development 1 32.04 Quite Low
Heart Rate Under Development 1 31.32 Quite Low
INFLAMMATION 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We speculate that the down-regulation of beta-adrenoceptor induced by the sympathomimetic action of amphetamine, might be a major cause of refractory hypotension.
Negative_regulation (down-regulation) of Positive_regulation (induced) of beta-adrenoceptor associated with pressure volume 2 under development
1) Confidence 0.38 Published 2001 Journal Masui Section Abstract Doc Link 11758335 Disease Relevance 0.17 Pain Relevance 0.37
Our results show that activation of the beta-adrenergic receptor inhibits myocardial production of TNF-alpha.
Negative_regulation (inhibits) of Positive_regulation (activation) of beta-adrenergic receptor
2) Confidence 0.16 Published 2000 Journal Am Surg Section Abstract Doc Link 11261622 Disease Relevance 0.15 Pain Relevance 0.09
Normal aging impairs upregulation of the beta-adrenergic but not the alpha-adrenergic response: aging and adrenergic upregulation.
Negative_regulation (impairs) of Positive_regulation (upregulation) of beta-adrenergic associated with aging
3) Confidence 0.01 Published 2006 Journal J. Cardiovasc. Pharmacol. Section Title Doc Link 17086093 Disease Relevance 0.20 Pain Relevance 0.09

General Comments

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