INT94455

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Context Info
Confidence 0.59
First Reported 2001
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.72
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CD33) cell adhesion (CD33) plasma membrane (CD33)
cell-cell signaling (CD33)
Anatomy Link Frequency
macrophages 1
fat 1
CD33 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 87 98.68 Very High Very High Very High
carpal tunnel syndrome 1 86.64 High High
cytokine 15 79.84 Quite High
Pain 3 78.00 Quite High
Inflammation 10 75.52 Quite High
Multiple sclerosis 1 67.12 Quite High
psoriasis 1 64.84 Quite High
chemokine 4 42.88 Quite Low
alcohol 1 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 87 98.68 Very High Very High Very High
Cancer 5 96.68 Very High Very High Very High
Necrosis 4 96.44 Very High Very High Very High
Leukemia 4 93.60 High High
Myeloid Leukemia 1 92.80 High High
Amyloid Plaque 3 92.76 High High
Hyperplasia 1 90.32 High High
Disease 5 88.24 High High
Arthropathy 1 88.24 High High
Carpal Tunnel Syndrome 1 86.64 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunohistochemical staining reveals that macrophages in tenosynovial tissues express CD13, CD14, CD33, HLA-DR, and CD68 antigens on their surfaces and express interleukin (IL)-1 beta, tumor necrosis factor (TNF)-alpha, and IL-6.
Gene_expression (express) of CD33 in macrophages associated with necrosis and cancer
1) Confidence 0.59 Published 2001 Journal Semin Dial Section Abstract Doc Link 11264784 Disease Relevance 0.84 Pain Relevance 0.12
His skin specimen revealed infiltration in the dermis and subcutaneous fat tissue by leukemic cells that were positive for the leukocyte common antigen (LCA, CD45), CD15, CD33, CD68, and HLA-DR.
Gene_expression (positive) of CD33 in fat
2) Confidence 0.58 Published 2001 Journal Leuk. Lymphoma Section Abstract Doc Link 11426568 Disease Relevance 0.77 Pain Relevance 0.08
We have previously shown that the effector site in RA synovial tissue is enriched in differentiated myeloid DCs, which express CD33, CD11c, MHC and costimulatory molecules, and nuclear RelB [21,25].
Gene_expression (express) of CD33 associated with rheumatoid arthritis
3) Confidence 0.35 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1065313 Disease Relevance 1.12 Pain Relevance 0.47

General Comments

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