INT94456

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Context Info
Confidence 0.36
First Reported 2000
Last Reported 2009
Negated 1
Speculated 1
Reported most in Abstract
Documents 3
Total Number 4
Disease Relevance 2.71
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (CD1A) plasma membrane (CD1A)
Anatomy Link Frequency
histiocytes 1
leukocyte 1
CD1A (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 2 93.12 High High
agonist 1 88.28 High High
Central nervous system 6 85.44 High High
headache 1 77.72 Quite High
Inflammation 34 72.64 Quite High
Pain 2 45.32 Quite Low
vincristine 1 34.16 Quite Low
Angina 1 25.00 Low Low
tolerance 1 25.00 Low Low
chemokine 18 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pressure Volume 2 Under Development 1 97.08 Very High Very High Very High
Cancer 4 96.96 Very High Very High Very High
Reperfusion Injury 1 96.20 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 95.40 Very High Very High Very High
Disease 11 94.84 High High
Fibrosis 2 93.12 High High
Langerhans-cell Histiocytosis 31 90.20 High High
Eosinophilic Granuloma 1 86.04 High High
Paraplegia 1 79.12 Quite High
Disease Progression 1 78.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The presence of Birbeck granules on electron microscopic examination or of antigenic markers that react with CD1a glycoprotein and the cytoplasmic protein S100 detected by immunostain is considered diagnostic, as shown in the present case.
CD1a Spec (examination) Binding (react) of
1) Confidence 0.36 Published 2006 Journal BMC Urol Section Body Doc Link PMC1634755 Disease Relevance 1.07 Pain Relevance 0.03
By immunohistochemical analysis, the characteristic histiocytes were positive for S100 protein and CD68 and negative for CD1a.
CD1a Binding (negative) of in histiocytes
2) Confidence 0.21 Published 2001 Journal Mod. Pathol. Section Abstract Doc Link 11266522 Disease Relevance 1.02 Pain Relevance 0.41
Importantly, HMB-PP and isopentenyl pyrophosphate do not require presentation by human leukocyte antigen (HLA) class I and II molecules or CD1 [18], supporting a sentinel function of V?
CD1 Neg (not) Binding (presentation) of in leukocyte
3) Confidence 0.11 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2637987 Disease Relevance 0.23 Pain Relevance 0.04
Denitrifying bacteria such as Paracoccus denitrificans have a membrane bound set of cytochromes (cyt cd1, cyt bc) which were shown to be involved in nitrite reduction activities.
cd1 Binding (bound) of
4) Confidence 0.06 Published 2000 Journal Acta Biochim. Pol. Section Abstract Doc Link 11996114 Disease Relevance 0.38 Pain Relevance 0

General Comments

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