INT94524

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Context Info
Confidence 0.39
First Reported 2001
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 1.66
Pain Relevance 1.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (MT1A) cytoplasm (MT1A)
Anatomy Link Frequency
inflection 1
bladder 1
MT1A (Homo sapiens)
Pain Link Frequency Relevance Heat
withdrawal 6 99.44 Very High Very High Very High
antidepressant 42 99.32 Very High Very High Very High
depression 57 94.12 High High
methadone 2 89.96 High High
opiate 7 88.48 High High
Duloxetine 1 88.48 High High
fluoxetine 1 88.00 High High
interstitial cystitis 1 84.84 Quite High
corticosteroid 2 5.00 Very Low Very Low Very Low
aspirin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Substance Withdrawal Syndrome 1 99.60 Very High Very High Very High
Bladder Cancer 9 98.80 Very High Very High Very High
Cancer 2 97.24 Very High Very High Very High
Depression 78 94.12 High High
Carcinoma In Situ 1 89.20 High High
Interstitial Cystitis 1 84.84 Quite High
Cystitis 1 83.80 Quite High
Attention Deficit Hyperactivity Disorder 1 83.44 Quite High
Bladder Disease 1 83.08 Quite High
Aging 14 15.44 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fig. 4 suggests that the PRC inflection from delay to advance occurred earlier in reference to the aMT6s acrophase among the older adults.
Gene_expression (acrophase) of aMT6s in inflection
1) Confidence 0.39 Published 2007 Journal J Circadian Rhythms Section Body Doc Link PMC1988787 Disease Relevance 0 Pain Relevance 0
The amplitude of the aMT6s PRC (Fig. 4, 5) was approximately 6 h, ranging from the maximal delay to the maximal advance in the averaged curves.
Gene_expression (amplitude) of aMT6s
2) Confidence 0.39 Published 2007 Journal J Circadian Rhythms Section Body Doc Link PMC1988787 Disease Relevance 0 Pain Relevance 0
A significant correlation between individual withdrawal symptom score severity and aMT6S excretion was demonstrated during stabilisation (r=.68, P<.05) and on Day 6 of treatment (r=.62, P<.05).
Gene_expression (excretion) of aMT6S associated with withdrawal
3) Confidence 0.37 Published 2002 Journal Prog. Neuropsychopharmacol. Biol. Psychiatry Section Abstract Doc Link 12188099 Disease Relevance 0.18 Pain Relevance 0.99
After treatment, aMT6s levels increased after antidepressants (P < 0.01), but not after placebo (P > 0.05).
Gene_expression (levels) of aMT6s associated with antidepressant
4) Confidence 0.23 Published 2009 Journal J. Psychopharmacol. (Oxford) Section Abstract Doc Link 18562432 Disease Relevance 0.35 Pain Relevance 0.67
The MT-1 and MT-2 proteins are encoded by a family of eight genes (MT-1A, MT-1B, MT-1E, MT-1F, MT-1G, MT-IH, MT-1X, and MT-2A), and reverse transcriptase-polymerase chain reaction was used to determine which genes were expressed in the normal bladder and in bladder cancer.
Gene_expression (expressed) of MT-1A in bladder associated with bladder cancer
5) Confidence 0.09 Published 2001 Journal Cancer Detect. Prev. Section Abstract Doc Link 11270423 Disease Relevance 1.12 Pain Relevance 0.08
The aMT6s duration was defined as the interval between onset and offset times.
Gene_expression (duration) of aMT6s
6) Confidence 0.09 Published 2005 Journal BMC Psychiatry Section Body Doc Link PMC1298312 Disease Relevance 0 Pain Relevance 0
Then 24-hour least-squares cosine fits were computed for each aMT6s collection, yielding mesors and acrophases.
Gene_expression (collection) of aMT6s
7) Confidence 0.09 Published 2005 Journal BMC Psychiatry Section Body Doc Link PMC1298312 Disease Relevance 0 Pain Relevance 0

General Comments

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