INT94526

Context Info Confidence 0.33 First Reported 2001 Last Reported 2001 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 1.90 Pain Relevance 0.15

transferase activity, transferring glycosyl groups (ALG1) endoplasmic reticulum (ALG1)

Anatomy Link Frequency bladder 4 ALG1 (Homo sapiens)

Pain Link Frequency Relevance Heat interstitial cystitis 2 98.04

Disease Link Frequency Relevance Heat Bladder Cancer 18 99.44 Carcinoma In Situ 2 99.24 Cancer 4 98.44 Interstitial Cystitis 2 98.04 Cystitis 2 97.00 Bladder Disease 2 96.28

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These studies suggest that the overexpression of MT-1/2 protein in bladder cancer is a result of the overexpression of the MT-1X gene.

Positive_regulation (overexpression) of Gene_expression (overexpression) of MT-1 in bladder associated with bladder cancer

1) Confidence 0.33 Published 2001 Journal Cancer Detect. Prev. Section Abstract Doc Link 11270423 Disease Relevance 1.01 Pain Relevance 0.05

Immunohistochemical analysis demonstrated that MT-1/2 was overexpressed in all samples of carcinoma in situ and in high-grade bladder cancer, with variable overexpression in low-grade bladder cancer and dysplastic lesions.

Positive_regulation (overexpressed) of Gene_expression (overexpressed) of MT-1 in bladder associated with bladder cancer and carcinoma in situ

2) Confidence 0.33 Published 2001 Journal Cancer Detect. Prev. Section Abstract Doc Link 11270423 Disease Relevance 0.88 Pain Relevance 0.10

General Comments

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