INT94541

Context Info Confidence 0.44 First Reported 2001 Last Reported 2001 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 1.84 Pain Relevance 0.06

nucleus (MT1X) cytoplasm (MT1X)

Anatomy Link Frequency bladder 4 MT1X (Homo sapiens)

Pain Link Frequency Relevance Heat interstitial cystitis 2 64.52

Disease Link Frequency Relevance Heat Bladder Cancer 18 99.60 Cancer 4 95.64 Carcinoma In Situ 2 68.88 Interstitial Cystitis 2 64.52 Cystitis 2 63.48 Bladder Disease 2 62.76

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These studies suggest that the overexpression of MT-1/2 protein in bladder cancer is a result of the overexpression of the MT-1X gene.

Positive_regulation (overexpression) of Gene_expression (overexpression) of MT-1X in bladder associated with bladder cancer

1) Confidence 0.44 Published 2001 Journal Cancer Detect. Prev. Section Abstract Doc Link 11270423 Disease Relevance 0.83 Pain Relevance 0

Comparison of expression relative to that of beta-actin demonstrated that the level of MT-1X mRNA was overexpressed greatly in bladder cancer as compared to the level in normal bladder tissue.

Positive_regulation (overexpressed) of Gene_expression (overexpressed) of MT-1X in bladder associated with bladder cancer

2) Confidence 0.31 Published 2001 Journal Cancer Detect. Prev. Section Abstract Doc Link 11270423 Disease Relevance 1.01 Pain Relevance 0.06

General Comments

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