INT94640

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Context Info
Confidence 0.04
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 1.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Gnai1) GTPase activity (Gnai1) cytoplasm (Gnai1)
signal transducer activity (Gnai1) signal transduction (Gnai1) nucleus (Gnai1)
Gnai1 (Mus musculus)
Pain Link Frequency Relevance Heat
mu opioid receptor 1 99.00 Very High Very High Very High
agonist 3 98.08 Very High Very High Very High
antinociception 4 89.28 High High
Morphine 5 87.84 High High
Buprenorphine 4 87.28 High High
methadone 4 86.68 High High
Opioid 3 85.96 High High
Analgesic 2 79.68 Quite High
opioid receptor 2 75.00 Quite High
analgesia 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 1 75.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression of alpha-subunits of Gi-protein classes, Gi1, Gi2, Gi3, Go1, Go2 and Gz, and those of the Gq-protein family, Gq and G11, was reduced by administration of antisense oligodeoxynucleotides (ODNs) complementary to sequences in their respective mRNAs.
Gene_expression (expression) of Gi1
1) Confidence 0.04 Published 2001 Journal Brain Res. Bull. Section Abstract Doc Link 11275413 Disease Relevance 0.08 Pain Relevance 1.29

General Comments

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