INT94713

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Context Info
Confidence 0.45
First Reported 2001
Last Reported 2010
Negated 2
Speculated 1
Reported most in Body
Documents 11
Total Number 12
Disease Relevance 8.02
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CD34) cell proliferation (CD34) signal transduction (CD34)
extracellular region (CD34) cell adhesion (CD34) cell motility (CD34)
Anatomy Link Frequency
Leukocyte 1
CFU-GM 1
epithelium 1
stem cells 1
CD34 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 3 88.44 High High
headache 5 86.48 High High
abdominal pain 5 86.40 High High
Pain 3 75.60 Quite High
Dysuria 1 74.52 Quite High
Bile 9 55.52 Quite High
Chronic pancreatitis 4 49.52 Quite Low
Inflammation 35 40.48 Quite Low
agonist 6 40.08 Quite Low
ischemia 5 9.76 Low Low
Disease Link Frequency Relevance Heat
Cardiovascular Disease 23 100.00 Very High Very High Very High
Cancer 34 99.84 Very High Very High Very High
Muscular Dystrophy 140 99.40 Very High Very High Very High
Hemangiopericytoma 5 99.20 Very High Very High Very High
Malignant Neoplastic Disease 13 98.92 Very High Very High Very High
Solitary Fibrous Tumors 11 97.04 Very High Very High Very High
Thrombosis 6 95.28 Very High Very High Very High
Cyst 3 92.68 High High
Erythrocytosis 11 92.00 High High
Gallbladder Disease 1 91.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
All tumors showed immunoreactivity for CD34 and bcl-2.
Regulation (immunoreactivity) of CD34 associated with cancer
1) Confidence 0.45 Published 2007 Journal Brain Tumor Pathol Section Abstract Doc Link 18095142 Disease Relevance 1.17 Pain Relevance 0.13
Single doses (60-150 microg/kg) of Ro 25-8315 and multiple doses of Filgrastim had similar effects on ANC and CD34+, although Ro 25-8315 had a greater effect on CFU-GM.
Regulation (effects) of CD34 in CFU-GM
2) Confidence 0.44 Published 2001 Journal Am. J. Hematol. Section Abstract Doc Link 11279634 Disease Relevance 0 Pain Relevance 0
Immunohistochemistry was positive for Leukocyte Common Antigen and CD 34.
Regulation (positive) of CD 34 in Leukocyte
3) Confidence 0.44 Published 2007 Journal Journal of gastrointestinal and liver diseases : JGLD Section Abstract Doc Link 17410296 Disease Relevance 0.57 Pain Relevance 0.09
The tumor cells that reacted to antibodies directed against HepPar1, CAM 5.2, CK19 and scattered cells were immunoreactive for CD117, CD34, and CD56.
Regulation (immunoreactive) of CD34 associated with cancer
4) Confidence 0.43 Published 2005 Journal Mod. Pathol. Section Abstract Doc Link 15696116 Disease Relevance 0.68 Pain Relevance 0.08
Stratification with respect to the expression of CD45 indicates that specifically the CD45dimCD34+KDR+ cell population correlates with cardiovascular disease and is significantly regulated by statin treatment, suggesting that the CD45dim fraction contains the prognostic relevant EPC populations.
Regulation (regulated) of CD45dimCD34 associated with cardiovascular disease
5) Confidence 0.43 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2972200 Disease Relevance 0.50 Pain Relevance 0
Effectiveness of CD34 covered stents has been tested in a series of studies performed under the HEALING (Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth) program.
Regulation (Effectiveness) of CD34
6) Confidence 0.42 Published 2010 Journal J Angiogenes Res Section Body Doc Link PMC2834645 Disease Relevance 0.61 Pain Relevance 0
The immunohistochemical staining revealed an intense CD34 and bcl-2 immunoreactivity.
Regulation (immunoreactivity) of CD34
7) Confidence 0.26 Published 2004 Journal Yonsei Med. J. Section Abstract Doc Link 15227752 Disease Relevance 0.80 Pain Relevance 0.07
We demonstrated a marked increase of EPOR protein on the membrane of erythroid progenitors and report its role in deregulating CD34+ cells proliferation and differentiation.
Regulation (deregulating) of CD34
8) Confidence 0.26 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2916842 Disease Relevance 0.92 Pain Relevance 0.14
Moreover, we observed that the nature of the dystrophin gene mutation did not affect the levels of both CD133+CXCR4+CD34- and CD133+CXCR4+CD34+ cells in the DMD subjects analyzed in this study.
Neg (not) Regulation (affect) of CD34 associated with muscular dystrophy
9) Confidence 0.24 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2377332 Disease Relevance 0.78 Pain Relevance 0
Moreover, we observed that the nature of the dystrophin gene mutation did not affect the levels of both CD133+CXCR4+CD34- and CD133+CXCR4+CD34+ cells in the DMD subjects analyzed in this study.
Neg (not) Regulation (affect) of CD34 associated with muscular dystrophy
10) Confidence 0.24 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2377332 Disease Relevance 0.78 Pain Relevance 0
CD31 and CD34 immunoreactivity was not expressed by the cystic epithelium.
Regulation (immunoreactivity) of CD34 in epithelium
11) Confidence 0.21 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC3016302 Disease Relevance 1.23 Pain Relevance 0.08
Bone marrow cells are a mixed population of stem cells, immature and mature hematopoietic cells, thus we also examined the effect of spirulina on isolated human peripheral blood CD34+ stem cells (Fig. 6.B).
Spec (examined) Regulation (effect) of CD34 in stem cells
12) Confidence 0.09 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2864748 Disease Relevance 0 Pain Relevance 0

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