INT94881

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Context Info
Confidence 0.42
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.51
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (MUC16) extracellular region (MUC16) cell adhesion (MUC16)
plasma membrane (MUC16)
Anatomy Link Frequency
eye 2
pleural fluid 2
MUC16 (Homo sapiens)
Pain Link Frequency Relevance Heat
Thoracotomy 1 98.80 Very High Very High Very High
Dismenorea 4 95.88 Very High Very High Very High
Angina 1 95.72 Very High Very High Very High
endometriosis 99 95.56 Very High Very High Very High
agonist 1 82.44 Quite High
pain pelvic 2 76.48 Quite High
imagery 2 67.08 Quite High
Pain 2 18.48 Low Low
Inflammation 23 7.76 Low Low
cytokine 20 6.72 Low Low
Disease Link Frequency Relevance Heat
Syndrome 49 99.68 Very High Very High Very High
Dry Eye 23 99.56 Very High Very High Very High
Cancer 16 97.20 Very High Very High Very High
Respiratory Distress 1 96.72 Very High Very High Very High
Endometriosis 126 95.88 Very High Very High Very High
Angina 1 95.72 Very High Very High Very High
Teratoma 2 92.36 High High
Rupture 1 90.84 High High
Sjoegrens Syndrome 31 90.68 High High
Reprotox - General 3 7 77.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The serum and pleural fluid levels of carcinoembryonic antigens, CA-125 and CA19-9 were invariably elevated, then decreased to normal range after the surgical resection.
Negative_regulation (decreased) of Gene_expression (levels) of CA-125 in pleural fluid
1) Confidence 0.42 Published 2001 Journal Pediatr Hematol Oncol Section Abstract Doc Link 11293292 Disease Relevance 0.62 Pain Relevance 0.15
In this cohort, patients with an improved (decreased) serum CA125 levels at 3 months (stratum 2) had a significantly better survival than those with deteriorated (increased) serum CA125 levels at 3 months (stratum 3).
Negative_regulation (decreased) of Gene_expression (levels) of CA125
2) Confidence 0.41 Published 2010 Journal J Ovarian Res Section Body Doc Link PMC2959041 Disease Relevance 0.07 Pain Relevance 0
Danjo et al. [33], using histochemical staining of surface conjunctival epithelial cells gathered from impression cytology, noted reduced expression of MUC16 in non-SS dry eye and observed that this was associated with rose bengal staining.
Negative_regulation (reduced) of Gene_expression (expression) of MUC16 in eye associated with syndrome and dry eye
3) Confidence 0.36 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2927371 Disease Relevance 1.06 Pain Relevance 0
Indeed, the immunologic effects of danazol have been studied in women with endometriosis and adenomyosis and include a decrease in serum immunoglobulins [67,68], a decrease in serum C3, a rise in serum C4 levels [68], decreased serum levels of autoantibodies against various phospholipid antigens [67,68], and decreased serum levels of CA125 during treatment [69-72].
Negative_regulation (decreased) of Gene_expression (levels) of CA125 associated with endometriosis and dismenorea
4) Confidence 0.05 Published 2003 Journal Reprod Biol Endocrinol Section Body Doc Link PMC305339 Disease Relevance 0.75 Pain Relevance 0.46

General Comments

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