INT94892

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Context Info
Confidence 0.31
First Reported 2000
Last Reported 2007
Negated 0
Speculated 0
Reported most in Title
Documents 7
Total Number 7
Disease Relevance 2.99
Pain Relevance 1.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (NOSTRIN) cytoplasmic membrane-bounded vesicle (NOSTRIN) plasma membrane (NOSTRIN)
cytoskeleton (NOSTRIN) cytoplasm (NOSTRIN)
Anatomy Link Frequency
macrophages 1
coronary artery 1
endothelial cell 1
basilar artery 1
NOSTRIN (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 2 100.00 Very High Very High Very High
Serotonin 2 97.60 Very High Very High Very High
Dismenorea 5 96.00 Very High Very High Very High
Inflammation 70 91.92 High High
Inflammatory mediators 4 90.16 High High
anesthesia 1 88.36 High High
Angina 46 84.88 Quite High
Potency 1 82.12 Quite High
cINOD 10 76.92 Quite High
cytokine 40 75.36 Quite High
Disease Link Frequency Relevance Heat
Hyperemia 6 99.44 Very High Very High Very High
Coronary Artery Disease 17 98.08 Very High Very High Very High
INFLAMMATION 92 97.12 Very High Very High Very High
Dysmenorrhea 5 96.00 Very High Very High Very High
Atherosclerosis 31 87.76 High High
Cv General 3 Under Development 42 84.88 Quite High
Cardiovascular Disease 12 76.32 Quite High
Hemorrhage 3 74.20 Quite High
Toxicity 2 73.68 Quite High
Disorder Of Lipid Metabolism 2 64.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Localization of endothelial nitric oxide synthase messenger ribonucleic acid by in situ hybridization in ectopic endometrial tissue in patients with adenomyosis.
Regulation (Localization) of endothelial nitric oxide synthase associated with dismenorea
1) Confidence 0.31 Published 2000 Journal Reprod. Fertil. Dev. Section Title Doc Link 11451019 Disease Relevance 0.34 Pain Relevance 0.40
Cyclooxygenase and nitric oxide synthase dependence of cutaneous reactive hyperemia in humans.
Regulation (dependence) of nitric oxide synthase associated with addiction and hyperemia
2) Confidence 0.28 Published 2007 Journal Am. J. Physiol. Heart Circ. Physiol. Section Title Doc Link 17369458 Disease Relevance 0.38 Pain Relevance 0.16
In this regard, statins are potent upregulators of endothelial cell nitric oxide synthase levels and nitric oxide synthesis.
Regulation (upregulators) of endothelial cell nitric oxide synthase in endothelial cell
3) Confidence 0.06 Published 2003 Journal Thromb J Section Body Doc Link PMC179880 Disease Relevance 0.68 Pain Relevance 0.09
Critical role of endothelial nitric oxide synthase and cyclooxygenase in response of rabbit basilar artery to serotonin.
Regulation (role) of endothelial nitric oxide synthase in basilar artery associated with serotonin
4) Confidence 0.03 Published 2002 Journal Jpn. J. Pharmacol. Section Title Doc Link 12396029 Disease Relevance 0 Pain Relevance 0.19
Influence of an inducible nitric oxide synthase promoter variant on clinical variables in patients with coronary artery disease.
Regulation (Influence) of nitric oxide synthase promoter in coronary artery associated with coronary artery disease
5) Confidence 0.01 Published 2001 Journal Clin. Sci. Section Title Doc Link 11294696 Disease Relevance 0.51 Pain Relevance 0.13
Lornoxicam also inhibited the formation of nitric oxide in RAW264.7 mouse macrophages stimulated with endotoxin, indicating an effect on inducible nitric oxide synthase [18].
Regulation (effect) of nitric oxide synthase in macrophages
6) Confidence 0.01 Published 2004 Journal Crit Care Section Body Doc Link PMC1065065 Disease Relevance 0.63 Pain Relevance 0.42
One possible explanation to this delay may be an up-regulation of the endothelial nitric oxide synthase, the major source of endothelial nitric oxide [22].
Regulation (regulation) of endothelial nitric oxide synthase
7) Confidence 0.01 Published 2006 Journal BMC Cardiovasc Disord Section Body Doc Link PMC1513599 Disease Relevance 0.44 Pain Relevance 0.33

General Comments

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