INT95045

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Context Info
Confidence 0.34
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oprl1) plasma membrane (Oprl1) molecular_function (Commd3)
cellular_component (Commd3) signal transducer activity (Oprl1) biological_process (Commd3)
Commd3 (Mus musculus)
Oprl1 (Mus musculus)
Pain Link Frequency Relevance Heat
orphanin 2 100.00 Very High Very High Very High
Opioid 2 100.00 Very High Very High Very High
Buprenorphine 15 99.12 Very High Very High Very High
opiate 1 92.56 High High
Analgesic 1 90.24 High High
MU agonist 1 75.00 Quite High
Kappa opioid receptor 1 70.24 Quite High
agonist 5 42.48 Quite Low
Potency 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We now describe the binding of norBUP to opioid and nociceptin/orphanin FQ (ORL1) receptors, and its effects on [(35)S]guanosine-5'-O-(gamma-thio)triphosphate ([(35)S]GTP gamma S) binding mediated by opioid or ORL1 receptors and in the mouse acetic acid writhing test.
norBUP Binding (binding) of ORL1 associated with orphanin and opioid
1) Confidence 0.34 Published 2001 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 11303059 Disease Relevance 0 Pain Relevance 1.16

General Comments

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