INT95090

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Context Info
Confidence 0.67
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.28
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ASIC4)
Anatomy Link Frequency
dorsal root ganglia 1
ASIC4 (Homo sapiens)
Pain Link Frequency Relevance Heat
sodium channel 2 97.48 Very High Very High Very High
tissue acidosis 1 96.00 Very High Very High Very High
Pain 3 95.04 Very High Very High Very High
ASIC 6 94.68 High High
nociceptor 1 74.80 Quite High
Central nervous system 1 61.32 Quite High
Spinal cord 1 61.28 Quite High
Disease Link Frequency Relevance Heat
Cerebral Palsy 7 99.68 Very High Very High Very High
Acidosis 1 95.72 Very High Very High Very High
Pain 2 95.04 Very High Very High Very High
Neurological Disease 2 85.72 High High
Movement Disorders 1 81.36 Quite High
Dystonia 2 79.64 Quite High
Nociception 1 76.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, although the ASIC4 gene is physically mapped to the PDC locus, our data indicates that ASIC4 gene mutation is not the cause of PDC.
Gene_expression (mapped) of ASIC4 gene associated with cerebral palsy
1) Confidence 0.67 Published 2001 Journal Eur. J. Hum. Genet. Section Abstract Doc Link 11571555 Disease Relevance 1.01 Pain Relevance 0.26
Certain BNaC isoforms are expressed exclusively in dorsal root ganglia (DRG) and have been proposed to form the ion channels mediating tissue acidosis-induced pain.
Gene_expression (expressed) of BNaC in dorsal root ganglia associated with pain, acidosis and tissue acidosis
2) Confidence 0.13 Published 2001 Journal J. Neurosci. Section Abstract Doc Link 11306621 Disease Relevance 0.27 Pain Relevance 0.39

General Comments

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