INT95093

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Context Info
Confidence 0.43
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.04
Pain Relevance 1.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (ITIH4, IL1B) aging (IL1B) cell-cell signaling (IL1B)
cytoplasm (ITIH4) cytosol (IL1B) extracellular space (IL1B)
Anatomy Link Frequency
spinal 1
ITIH4 (Homo sapiens)
IL1B (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 3 99.72 Very High Very High Very High
intrathecal 4 97.74 Very High Very High Very High
Spinal cord 3 94.20 High High
cytokine 5 92.64 High High
Pain 8 91.28 High High
allodynia 2 70.88 Quite High
Hyperalgesia 1 70.32 Quite High
Thermal hyperalgesia 1 59.56 Quite High
Disease Link Frequency Relevance Heat
Pain 6 86.72 High High
Necrosis 1 81.64 Quite High
Cancer 1 81.28 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 4 75.00 Quite High
Neuropathic Pain 2 70.88 Quite High
Hyperalgesia 2 70.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intrathecal administration of fluorocitrate (a glial metabolic inhibitor), TNF antagonist, and IL-1 antagonist each blocked gp120-induced increases in spinal IL-1 protein.
gp120-induced Positive_regulation (increases) of IL-1 in spinal associated with antagonist and intrathecal
1) Confidence 0.43 Published 2001 Journal J. Neurosci. Section Abstract Doc Link 11306633 Disease Relevance 1.04 Pain Relevance 1.32

General Comments

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