INT95231

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Context Info
Confidence 0.53
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0.40
Pain Relevance 1.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transferase activity, transferring acyl groups (Aanat) cytoplasm (Aanat)
Anatomy Link Frequency
brain 3
Aanat (Mus musculus)
Pain Link Frequency Relevance Heat
Serotonin 9 98.76 Very High Very High Very High
antidepressant 9 94.36 High High
depression 9 92.24 High High
Hippocampus 3 88.88 High High
fluoxetine 3 86.52 High High
Disease Link Frequency Relevance Heat
Depression 9 92.24 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this study, we investigated whether AANAT mRNA is expressed in the brain of C57BL/6J and C3H/HeJ mice and whether those mice differ behaviorally, i.e., in a forced swimming test which is used to evaluate antidepressant drugs (such drugs shorten the time of immobility).
Transcription (expressed) of AANAT in brain associated with antidepressant
1) Confidence 0.53 Published 2001 Journal J. Pineal Res. Section Abstract Doc Link 11316327 Disease Relevance 0.16 Pain Relevance 0.45
We found that C3H/HeJ mice express in the brain normal AANAT mRNA, whereas C57BL/6J mice express mutated AANAT mRNA.
Transcription (express) of AANAT in brain
2) Confidence 0.53 Published 2001 Journal J. Pineal Res. Section Abstract Doc Link 11316327 Disease Relevance 0.17 Pain Relevance 0.45
AANAT mRNA is expressed in the pineal gland and retina, and also in the rat brain.
Transcription (expressed) of AANAT in brain
3) Confidence 0.53 Published 2001 Journal J. Pineal Res. Section Abstract Doc Link 11316327 Disease Relevance 0.07 Pain Relevance 0.38

General Comments

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