INT95252

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Context Info
Confidence 0.03
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.73
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
dorsal root ganglion 2
IER3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 5 99.58 Very High Very High Very High
dorsal root ganglion 2 94.56 High High
Antinociceptive 4 91.60 High High
Spinal cord 1 85.28 High High
Dorsal horn 1 84.68 Quite High
opiate 1 82.20 Quite High
Analgesic 1 67.36 Quite High
tolerance 1 62.72 Quite High
intrathecal 1 57.60 Quite High
Pain 1 45.60 Quite Low
Disease Link Frequency Relevance Heat
Cytomegalovirus Infection 1 100.00 Very High Very High Very High
Cold Sores 2 99.68 Very High Very High Very High
Herpes Simplex Virus 2 97.16 Very High Very High Very High
Ganglion Cysts 2 94.56 High High
Nociception 1 86.72 High High
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We transfected neurons of the dorsal root ganglion in vivo by footpad inoculation with 30 microl (3 x 10(7) p.f.u.) of a replication-incompetent (ICP4-deleted) herpes simplex virus (HSV) vector with a cassette containing a portion of the human proenkephalin gene coding for 5 met- and 1 leu-enkephalin molecules under the control of the human cytomegalovirus immediate-early promoter (HCMV IEp) inserted in the HSV thymidine kinase (tk) locus.
Regulation (control) of Positive_regulation (inserted) of immediate-early promoter in dorsal root ganglion associated with ganglion cysts, dorsal root ganglion, cold sores, herpes simplex virus, cytomegalovirus infection and enkephalin
1) Confidence 0.03 Published 2001 Journal Gene Ther. Section Abstract Doc Link 11319622 Disease Relevance 0.73 Pain Relevance 0.78

General Comments

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