INT95273

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Context Info
Confidence 0.20
First Reported 2001
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.85
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Nos3) aging (Nos3) Golgi apparatus (Nos3)
cytoplasm (Nos3) signal transduction (Nos3) oxidoreductase activity (Nos3)
Nos3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cINOD 7 98.62 Very High Very High Very High
aspirin 6 81.32 Quite High
bradykinin 3 40.40 Quite Low
Dopamine 7 5.00 Very Low Very Low Very Low
nMDA receptor 6 5.00 Very Low Very Low Very Low
Glutamate 4 5.00 Very Low Very Low Very Low
Potency 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
addiction 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 3 99.08 Very High Very High Very High
Ulcers 8 98.28 Very High Very High Very High
Injury 2 93.00 High High
INFLAMMATION 5 75.00 Quite High
Cv Unclassified Under Development 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The impairment in buccal mucosal ulcer healing by NSAID ingestion is manifested in up-regulation in the expression of ECE-1 responsible for ET-1 generation, suppression in cNOS, and amplification of apoptotic events that delay the healing process.
Regulation (responsible) of Negative_regulation (suppression) of cNOS associated with ulcers, cinod and apoptosis
1) Confidence 0.20 Published 2001 Journal J. Physiol. Pharmacol. Section Abstract Doc Link 11321515 Disease Relevance 0.85 Pain Relevance 0.37
M, there was no effect of eNOS or nNOS inhibition on basal O2 consumption or on O2 consumption following stimulation of these NO synthases, and the NO concentration was estimated to be below 6–22 nM [84].
Neg (no) Regulation (effect) of Negative_regulation (inhibition) of eNOS
2) Confidence 0.17 Published 2009 Journal Nitric Oxide Section Body Doc Link PMC2779337 Disease Relevance 0 Pain Relevance 0

General Comments

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