INT9528

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Context Info
Confidence 0.50
First Reported 1985
Last Reported 1992
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.14
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Agt, Pomc) extracellular region (Agt, Pomc) aging (Agt)
extracellular matrix organization (Agt) cell-cell signaling (Pomc) cytoplasm (Pomc)
Agt (Rattus norvegicus)
Pomc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Catecholamine 1 81.28 Quite High
Kinase C 4 80.32 Quite High
Opioid 1 60.36 Quite High
Morphine 1 45.36 Quite Low
antagonist 2 25.00 Low Low
medulla 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Stress 8 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PMA, OAG, AVP, and Ang II stimulated IR-beta-endorphin secretion.
Ang II Positive_regulation (stimulated) of Localization (secretion) of IR-beta-endorphin
1) Confidence 0.50 Published 1992 Journal Brain Res. Bull. Section Abstract Doc Link 1422853 Disease Relevance 0 Pain Relevance 0.21
In addition to corticotropin-releasing factor (CRF) and structurally related peptides, arginine vasopressin (AVP), oxytocin, angiotensin II, vasoactive intestinal polypeptide, peptide histidine isoleucinamide, epinephrine (E), and norepinephrine induce secretion of adrenocorticotropin (ACTH) from corticotropic cells in vitro.
angiotensin II Positive_regulation (induce) of Localization (secretion) of adrenocorticotropin
2) Confidence 0.01 Published 1985 Journal Fed. Proc. Section Abstract Doc Link 2981737 Disease Relevance 0.14 Pain Relevance 0.04

General Comments

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