INT95308

Context Info Confidence 0.00 First Reported 2001 Last Reported 2001 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.08 Pain Relevance 0

DNA binding (RELA, Nfkb1) cytoplasm (RELA, Nfkb1) cytosol (RELA, Nfkb1) nucleus (RELA, Nfkb1) nucleoplasm (RELA) mitochondrion (Nfkb1)

Anatomy Link Frequency bone marrow 1 RELA (Homo sapiens) Nfkb1 (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 1 43.52 qutenza 1 25.00

Disease Link Frequency Relevance Heat Adhesions 2 77.08

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Culture of bone marrow stromal cells in VP-16 resulted in reduced nuclear RelA (p65), a modest increase in nuclear NF-kappaB1 (p50), and reduced NF-kappaB binding to its DNA consensus sequence.

nuclear RelA Binding (binding) of NF-kappaB in bone marrow

1) Confidence 0.00 Published 2001 Journal Biochem. Pharmacol. Section Abstract Doc Link 11322928 Disease Relevance 0.08 Pain Relevance 0

General Comments

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