INT95318

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Context Info
Confidence 0.22
First Reported 2001
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 17
Total Number 19
Disease Relevance 21.26
Pain Relevance 20.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
sciatic nerve 1
knee joint 1
paw 1
Pain1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 1533 100.00 Very High Very High Very High
Lasting pain 42 100.00 Very High Very High Very High
Cancer pain 27 100.00 Very High Very High Very High
Sciatic nerve 5 99.98 Very High Very High Very High
Duloxetine 168 99.90 Very High Very High Very High
Arthritis 630 99.76 Very High Very High Very High
diabetic neuropathy 20 99.76 Very High Very High Very High
Analgesic 137 99.00 Very High Very High Very High
Somatic pain 4 98.02 Very High Very High Very High
alcohol 2 95.44 Very High Very High Very High
Disease Link Frequency Relevance Heat
Pain 1587 100.00 Very High Very High Very High
Arthralgia 78 100.00 Very High Very High Very High
Cancer Pain 27 100.00 Very High Very High Very High
Arthritis 690 99.76 Very High Very High Very High
Diabetic Neuropathy 30 99.76 Very High Very High Very High
Diabetes Mellitus 24 99.76 Very High Very High Very High
Peripheral Neuropathy 4 99.40 Very High Very High Very High
Cognitive Disorder 25 97.76 Very High Very High Very High
Anxiety Disorder 34 96.72 Very High Very High Very High
Disease 100 93.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Most significant were associations with SSCP markers derived from the Pain-1 gene on chromosome III [25].
Pain-1 Binding (associations) of associated with pain
1) Confidence 0.22 Published 2010 Journal BMC Plant Biol Section Body Doc Link PMC3012049 Disease Relevance 0.28 Pain Relevance 0.19
The weak association of SSCP marker Pain1-5d with tuber starch content was confirmed by the corresponding SNP allele T741 (Table 5).
Pain1 Binding (association) of
2) Confidence 0.18 Published 2010 Journal BMC Plant Biol Section Body Doc Link PMC3012049 Disease Relevance 0.15 Pain Relevance 0.08
The clinical efficacy of duloxetine for pain associated with diabetic peripheral neuropathy has been demonstrated in three double-blind, placebo-controlled, randomized studies.
pain Binding (associated) of associated with pain, diabetic neuropathy, peripheral neuropathy and duloxetine
3) Confidence 0.14 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350145 Disease Relevance 0.61 Pain Relevance 0.70
The investigators in all three studies concluded that duloxetine 60 mg qd and 60 mg bid were effective for treating pain associated with diabetic neuropathy.
pain Binding (associated) of associated with pain, diabetic neuropathy and duloxetine
4) Confidence 0.14 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350145 Disease Relevance 1.08 Pain Relevance 1.19
We have therefore investigated this possibility in animals following partial sciatic nerve ligation (an animal model of chronic pain; Pain 43 (1990) 205).
pain Spec (partial) Binding (ligation) of in sciatic nerve associated with pain, lasting pain and sciatic nerve
5) Confidence 0.08 Published 2001 Journal Pain Section Abstract Doc Link 11323126 Disease Relevance 0.50 Pain Relevance 0.68
Pain was defined as and limited to somatic pain, i.e. a symptom generally relieved by analgesics, and consequently excluding what the pain expert interpreted as existential pain.


pain Binding (interpreted) of associated with pain, analgesic and somatic pain
6) Confidence 0.04 Published 2007 Journal BMC Geriatr Section Body Doc Link PMC2234400 Disease Relevance 1.15 Pain Relevance 0.93
The four-item severity subscale asks patients to rate their worst pain, least pain, average pain over the previous 24 hours, and pain right now.
pain Binding (rate) of associated with pain
7) Confidence 0.03 Published 2007 Journal Mol Pain Section Body Doc Link PMC1851005 Disease Relevance 1.81 Pain Relevance 1.90
The four-item severity subscale asks patients to rate their worst pain, least pain, average pain over the previous 24 hours, and pain right now.
pain Binding (rate) of associated with pain
8) Confidence 0.03 Published 2007 Journal Mol Pain Section Body Doc Link PMC1851005 Disease Relevance 1.80 Pain Relevance 1.90
The four-item severity subscale asks patients to rate their worst pain, least pain, average pain over the previous 24 hours, and pain right now.
pain Binding (rate) of associated with pain
9) Confidence 0.03 Published 2007 Journal Mol Pain Section Body Doc Link PMC1851005 Disease Relevance 1.88 Pain Relevance 1.92
The four-item severity subscale asks patients to rate their worst pain, least pain, average pain over the previous 24 hours, and pain right now.
pain Binding (rate) of associated with pain
10) Confidence 0.03 Published 2007 Journal Mol Pain Section Body Doc Link PMC1851005 Disease Relevance 1.79 Pain Relevance 1.89
This review will focus on knee joint pain associated with arthritis.
pain Binding (associated) of in knee joint associated with pain, arthralgia and arthritis
11) Confidence 0.03 Published 2007 Journal Mol Pain Section Abstract Doc Link PMC1851005 Disease Relevance 0.86 Pain Relevance 0.66
Measurements of knee joint pain associated with arthritis in animal models include indirect (weight bearing, gait analysis, spontaneous mobility, and sensitivity of the paw to von Frey filaments or heat) and more direct measurements (probing the sensitivity of the knee, knee extension angle, and vocalizations evoked by stimulation of the knee).
pain Binding (associated) of in paw associated with pain, arthralgia and arthritis
12) Confidence 0.03 Published 2007 Journal Mol Pain Section Body Doc Link PMC1851005 Disease Relevance 1.34 Pain Relevance 0.88
Although the means exist for its effective relief, childrenÂ’s pain is often not recognized or, if recognized, may be inadequately treated, even when sufficient resources are available [49, 50].
pain Binding (recognized) of associated with pain
13) Confidence 0.03 Published 2009 Journal The Open Biochemistry Journal Section Body Doc Link PMC2695605 Disease Relevance 1.38 Pain Relevance 0.93
The reliability and validity of behavioural observations are highest when the pain being measured is short in duration and acute in nature, such as pain associated with medical procedures.
pain Binding (associated) of associated with pain
14) Confidence 0.03 Published 2009 Journal The Open Biochemistry Journal Section Body Doc Link PMC2695605 Disease Relevance 0.98 Pain Relevance 0.91
Children have to accurately report on the location, sensory quality, intensity, affective elements and tolerability of pain.
pain Binding (tolerability) of associated with pain
15) Confidence 0.02 Published 2009 Journal The Open Biochemistry Journal Section Body Doc Link PMC2695605 Disease Relevance 1.20 Pain Relevance 1.07
Existing knowledge provides a basic approach for relieving cancer pain and chronic pain that can be implemented in developed and developing countries alike.
pain Binding (relieving) of associated with cancer pain and lasting pain
16) Confidence 0.02 Published 2009 Journal The Open Biochemistry Journal Section Body Doc Link PMC2695605 Disease Relevance 1.11 Pain Relevance 1.32
Existing knowledge provides a basic approach for relieving cancer pain and chronic pain that can be implemented in developed and developing countries alike.
pain Binding (relieving) of associated with cancer pain and lasting pain
17) Confidence 0.02 Published 2009 Journal The Open Biochemistry Journal Section Body Doc Link PMC2695605 Disease Relevance 1.05 Pain Relevance 1.31
Although the means exist for its effective relief, childrenÂ’s pain is often not recognized or, if recognized, may be inadequately treated, even when sufficient resources are available [49, 50].
pain Binding (recognized) of associated with pain
18) Confidence 0.02 Published 2009 Journal The Open Biochemistry Journal Section Body Doc Link PMC2695605 Disease Relevance 1.44 Pain Relevance 0.98
Sometimes, health structures show little understanding of adequate recognizing and facing problems related to children pain.
pain Binding (recognizing) of associated with pain
19) Confidence 0.02 Published 2009 Journal The Open Biochemistry Journal Section Body Doc Link PMC2695605 Disease Relevance 0.85 Pain Relevance 0.72

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