INT95324

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Context Info
Confidence 0.03
First Reported 2001
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.88
Pain Relevance 2.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (NPVF)
Anatomy Link Frequency
vascular system 1
peripheral nervous system 1
meninges 1
NPVF (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 34 100.00 Very High Very High Very High
Neuropeptide 24 100.00 Very High Very High Very High
calcitonin gene related peptide 16 100.00 Very High Very High Very High
Peripheral nervous system 1 99.74 Very High Very High Very High
c fibre 2 99.60 Very High Very High Very High
aspirin 8 99.08 Very High Very High Very High
neuralgia 4 99.08 Very High Very High Very High
trigeminal ganglion 2 98.44 Very High Very High Very High
headache 2 94.28 High High
Migraine 10 93.36 High High
Disease Link Frequency Relevance Heat
Hypersensitivity 38 98.78 Very High Very High Very High
Ganglion Cysts 2 98.00 Very High Very High Very High
Headache 12 94.28 High High
INFLAMMATION 5 91.60 High High
Neurogenic Inflammation 9 86.08 High High
Increased Venous Pressure Under Development 7 63.60 Quite High
Asthma 1 54.16 Quite High
Rhinitis 1 52.56 Quite High
Disease 5 5.52 Low Low
Conjunctiva Disease 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Calcitonin gene related peptide (CGRP) released from the C-fibers projecting from the trigeminal ganglion to the meninges has been suggested to play a crucial role in the pathophysiology of headache, particularly migraine.
Localization (released) of related peptide in meninges associated with ganglion cysts, c fibre, calcitonin gene related peptide, migraine, trigeminal ganglion and headache
1) Confidence 0.03 Published 2001 Journal Pain Section Abstract Doc Link 11323131 Disease Relevance 0.50 Pain Relevance 0.93
An in vivo rat model to study calcitonin gene related peptide release following activation of the trigeminal vascular system.
Localization (release) of related peptide in vascular system associated with aspirin and calcitonin gene related peptide
2) Confidence 0.03 Published 2001 Journal Pain Section Title Doc Link 11323131 Disease Relevance 0.69 Pain Relevance 1.56
Growing evidence is showing that allergic reactions are influenced by the peripheral nervous system through the release of neuromediators including substance P (SP), neuropeptide Y (NPY), vasoactive intestinal peptide (VIP), and calcitonine gene-related peptide (CGRP) [1-5].
Localization (release) of related peptide in peripheral nervous system associated with peripheral nervous system, hypersensitivity, neuropeptide and substance p
3) Confidence 0.02 Published 2011 Journal Molecular Vision Section Body Doc Link PMC3021574 Disease Relevance 0.69 Pain Relevance 0.44

General Comments

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