INT95408

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Context Info
Confidence 0.12
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Map3k1, Ephb1) endosome (Ephb1) signal transduction (Ephb1)
plasma membrane (Ephb1) cytoskeleton (Map3k1)
Map3k1 (Rattus norvegicus)
Ephb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 1 99.26 Very High Very High Very High
agonist 1 93.20 High High
opioid receptor 1 92.88 High High
ischemia 1 84.40 Quite High
Opioid 4 79.28 Quite High
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 1 84.40 Quite High
Stress 1 77.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The involvement of ERK was examined with PD 098059, a selective pharmacological antagonist which inhibits the upstream kinase, MEK-1, that phosphorylates and activates ERK.
MEK-1 Positive_regulation (activates) of ERK associated with antagonist
1) Confidence 0.12 Published 2001 Journal Basic Res. Cardiol. Section Abstract Doc Link 11327331 Disease Relevance 0.16 Pain Relevance 0.46

General Comments

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