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Context Info
Confidence 0.50
First Reported 2001
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.37
Pain Relevance 1.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Nefh)
Nefh (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 5 99.88 Very High Very High Very High
tolerance 1 98.00 Very High Very High Very High
Spinal cord 3 96.32 Very High Very High Very High
withdrawal 1 95.20 Very High Very High Very High
opiate 2 94.76 High High
cerebral cortex 2 92.00 High High
Sciatic nerve 3 90.00 High High
narcan 3 82.64 Quite High
addiction 2 82.24 Quite High
Opioid 2 81.84 Quite High
Disease Link Frequency Relevance Heat
Poisoning 2 83.44 Quite High
Opiate Addiction 1 82.24 Quite High
Neuropathic Pain 2 68.08 Quite High
Morphine Dependence 1 5.00 Very Low Very Low Very Low
Drug Induced Neurotoxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, 2 h after the last dose of morphine, the abundance of pNF-H was still increased (27%), which was followed (6-24 h) by down-regulation of pNF-H (5% increase at 6 h; 5% decrease at 12 h, and 29% decrease at 24 h).
Positive_regulation (increased) of Gene_expression (abundance) of pNF-H associated with morphine
1) Confidence 0.50 Published 2001 Journal Neurosci. Lett. Section Abstract Doc Link 11335049 Disease Relevance 0.08 Pain Relevance 1.27
The levels of NF-L and NF-H in serum significantly increased, while NF-M, alpha-tubulin, beta-tubulin and beta-actin contents remain unchanged.
Positive_regulation (increased) of Gene_expression (levels) of NF-H
2) Confidence 0.36 Published 2008 Journal Toxicology Section Abstract Doc Link 18177991 Disease Relevance 0.29 Pain Relevance 0.30

General Comments

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