INT95508

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Context Info
Confidence 0.59
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Ghr) extracellular space (Ghr) extracellular region (Ghr)
plasma membrane (Ghr) nucleus (Ghr) cytoplasm (Ghr)
Ghr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
opiate 1 98.22 Very High Very High Very High
Morphine 3 90.88 High High
Hippocampus 3 84.12 Quite High
Spinal cord 3 78.64 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This result indicates that the opiate does not only affect the receptor protein as shown earlier by binding studies, but also reduces the expression or turnover of the GHR as well as GHBP at the transcription level.
Negative_regulation (reduces) of Gene_expression (expression) of GHR associated with opiate
1) Confidence 0.59 Published 2001 Journal Neurosci. Lett. Section Abstract Doc Link 11335057 Disease Relevance 0 Pain Relevance 0.56

General Comments

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