INT95545

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Context Info
Confidence 0.04
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.97
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il10) signal transduction (Ptgir) extracellular region (Il10)
intracellular (Il10) plasma membrane (Ptgir) signal transducer activity (Ptgir)
Ptgir (Mus musculus)
Il10 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 4 99.52 Very High Very High Very High
Inflammation 5 92.68 High High
bradykinin 3 89.64 High High
antagonist 1 83.64 Quite High
cytokine 2 75.84 Quite High
Disease Link Frequency Relevance Heat
Pain 3 99.52 Very High Very High Very High
INFLAMMATION 4 92.68 High High
Pressure And Volume Under Development 4 89.00 High High
Hypersensitivity 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Production of TNF alpha and IL-10 was modified with PGI2 or PGE2; the production of TNF alpha was down-regulated by the stimulation via IP-, EP2- or EP4 receptor, but that of IL-10 was up-regulated by these receptors, resulting in an anti-inflammatory effect.
PGI2 Regulation (modified) of Gene_expression (Production) of IL-10 associated with inflammation
1) Confidence 0.04 Published 2001 Journal Nippon Yakurigaku Zasshi Section Abstract Doc Link 11338374 Disease Relevance 0.97 Pain Relevance 0.63

General Comments

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