INT95557

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Context Info
Confidence 0.09
First Reported 2001
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.41
Pain Relevance 1.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
brain 1
D2Mit212 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 7 99.96 Very High Very High Very High
Cannabinoid receptor 6 99.90 Very High Very High Very High
Cannabinoid 14 99.62 Very High Very High Very High
Kappa opioid receptor 1 98.68 Very High Very High Very High
Opioid 2 93.16 High High
opioid receptor 1 85.04 High High
alcohol 5 77.36 Quite High
antagonist 1 49.84 Quite Low
Substantia nigra 1 43.68 Quite Low
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Targeted Disruption 4 97.80 Very High Very High Very High
Sprains And Strains 5 93.52 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cannabinoid receptor and WIN 55 212-2-stimulated [35S]-GTPgammaS binding in the brain of mu-, delta- and kappa-opioid receptor knockout mice.
WIN 55 212-2 Binding (binding) of in brain associated with targeted disruption, cannabinoid receptor and kappa opioid receptor
1) Confidence 0.09 Published 2003 Journal Eur. J. Neurosci. Section Title Doc Link 14622180 Disease Relevance 0.16 Pain Relevance 0.65
The net CB1 receptor agonist (WIN55,212-2 or HU-210 or CP55,940)-stimulated [(35)S]GTPgammaS binding was reduced significantly (-10% to -12%, P < 0.05) in PM from DBA/2 mice; no significant differences were observed in basal [(35)S]GTPgammaS binding among these strains.
WIN55,212-2 Binding (binding) of associated with cannabinoid, agonist and sprains and strains
2) Confidence 0.03 Published 2001 Journal J. Neurosci. Res. Section Abstract Doc Link 11340650 Disease Relevance 0.25 Pain Relevance 0.69

General Comments

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