INT95564

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Context Info
Confidence 0.03
First Reported 2001
Last Reported 2001
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.70
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (HRAS, IL12A) Golgi apparatus (HRAS) GTPase activity (HRAS)
cytosol (HRAS) signal transduction (HRAS) extracellular space (IL12A)
HRAS (Homo sapiens)
IL12A (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 11 79.12 Quite High
cytokine 2 71.68 Quite High
interstitial cystitis 1 67.52 Quite High
Arthritis 1 66.48 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 10 79.12 Quite High
Interstitial Cystitis 1 67.52 Quite High
Arthritis 1 66.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We unexpectedly found that the induction of IL-12 and TNF-alpha by these HA preparations was not due to their degradation to low-molecular-weight fragments, since their native high-molecular-weight forms possessed the same ability to stimulate IL-12 and TNF-alpha synthesis, but was due to the presence of contaminating DNA.
Neg (not) Positive_regulation (due) of HA Positive_regulation (induction) of IL-12
1) Confidence 0.03 Published 2001 Journal J. Pharm. Pharmacol. Section Abstract Doc Link 11341374 Disease Relevance 0.70 Pain Relevance 0.45

General Comments

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