INT9559

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Context Info
Confidence 0.69
First Reported 1992
Last Reported 2005
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0.82
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Gnrh1) extracellular region (Gnrh1) molecular_function (Gnrh1)
Anatomy Link Frequency
neuron 2
Gnrh1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
noradrenaline 6 91.04 High High
Neurotransmitter 4 79.76 Quite High
agonist 4 75.36 Quite High
Dopamine 1 68.28 Quite High
Serotonin 2 65.12 Quite High
Morphine 1 63.80 Quite High
gABA 3 60.44 Quite High
opiate 2 57.88 Quite High
excitatory amino acid 1 54.48 Quite High
Central nervous system 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Precocious Puberty 86 95.72 Very High Very High Very High
Urological Neuroanatomy 13 93.36 High High
Disease 4 5.00 Very Low Very Low Very Low
Anaplastic Astrocytoma 2 5.00 Very Low Very Low Very Low
Central Nervous System Cancer 2 5.00 Very Low Very Low Very Low
Hamartoma 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, it seems that stimuli which evoke LHRH release also increase LHRH mRNA transcription to replenish the hormone released during the LH surge.
Spec (seems) Positive_regulation (increase) of Transcription (transcription) of LHRH mRNA
1) Confidence 0.69 Published 1992 Journal Ciba Found. Symp. Section Abstract Doc Link 1425026 Disease Relevance 0.08 Pain Relevance 0.62
In the present study, the high level of GnRH mRNA expression was observed in the M, but the number of the GnRH neuron decreased.
Positive_regulation (level) of Transcription (expression) of GnRH in neuron
2) Confidence 0.50 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1236957 Disease Relevance 0.33 Pain Relevance 0.04
The GnRH mRNA expression increased significantly in M compared with that in N and V (p < 0.05).


Positive_regulation (increased) of Transcription (expression) of GnRH
3) Confidence 0.46 Published 2005 Journal Reprod Biol Endocrinol Section Abstract Doc Link PMC1236957 Disease Relevance 0.41 Pain Relevance 0

General Comments

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