INT95695

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Context Info
Confidence 0.19
First Reported 2001
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.80
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Chrnb1) transport (Chrnb1) plasma membrane (Chrnb1)
neurological system process (Chrnb1)
Anatomy Link Frequency
muscle fiber 1
Chrnb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Neuronal nitric oxide synthase 2 99.80 Very High Very High Very High
cytokine 37 98.12 Very High Very High Very High
lidocaine 1 75.28 Quite High
fibrosis 1 53.12 Quite High
Inflammation 13 50.24 Quite High
Multiple sclerosis 2 33.60 Quite Low
Inflammatory response 1 24.00 Low Low
alcohol 1 12.96 Low Low
adenocard 11 5.00 Very Low Very Low Very Low
substance P 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Muscle Weakness 1 95.24 Very High Very High Very High
Disease 34 90.76 High High
Myasthenia Gravis 2 87.44 High High
Autoimmune Disease 8 82.28 Quite High
Neurodegenerative Disease 10 62.16 Quite High
Pulmonary Fibrosis 1 53.52 Quite High
Inflammatory Bowel Disease 1 50.24 Quite High
Asthma 1 43.84 Quite Low
Apoptosis 3 38.16 Quite Low
Multiple Sclerosis 4 33.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We investigated whether the changes in acetylcholine receptor (AChR) distribution and neuronal nitric oxide synthase (nNOS) expression reported for the skeletal muscle of mdx mice were a consequence of muscle fiber regeneration rather than of the absence of dystrophin.
Transcription (distribution) of AChR in muscle fiber associated with neuronal nitric oxide synthase
1) Confidence 0.19 Published 2001 Journal Muscle Nerve Section Abstract Doc Link 11353428 Disease Relevance 0 Pain Relevance 0.16
The effect of cytokines on acetylocholine receptor expression was studied by Poea-Guyon et al (2005), who found that AchR transcripts are up-regulated by IFN?
Transcription (transcripts) of AchR associated with cytokine
2) Confidence 0.05 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2654796 Disease Relevance 0.80 Pain Relevance 0.31

General Comments

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