INT95720

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Context Info
Confidence 0.80
First Reported 2001
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 2.04
Pain Relevance 2.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Calca) aging (Calca) extracellular region (Calca)
nucleus (Calca) intracellular (Calca) cytoplasm (Calca)
Anatomy Link Frequency
dorsal horns 2
Calca (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 11 100.00 Very High Very High Very High
Pain 10 97.92 Very High Very High Very High
MU agonist 1 96.88 Very High Very High Very High
addiction 3 96.56 Very High Very High Very High
chemokine 4 92.16 High High
Sumatriptan 1 90.76 High High
agonist 4 90.28 High High
Inflammation 11 88.08 High High
Neuropathic pain 6 86.08 High High
adenocard 7 82.36 Quite High
Disease Link Frequency Relevance Heat
Nociception 2 99.66 Very High Very High Very High
Pain 14 97.92 Very High Very High Very High
Cluster Headache 1 89.48 High High
Hypersensitivity 2 78.44 Quite High
Spinal Cord Injury 12 76.80 Quite High
Neuropathic Pain 8 75.00 Quite High
Injury 2 75.00 Quite High
INFLAMMATION 4 47.08 Quite Low
Syndrome 2 42.48 Quite Low
Headache 2 39.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Forskolin-stimulated CGRP release and CREB phosphorylation could be mimicked by incubation of the cells with chlorophenylthio-cAMP and blocked by pretreatment with the PKA inhibitor myrPKI(14-22).
Phosphorylation (phosphorylation) of CGRP associated with calcitonin gene-related peptide
1) Confidence 0.80 Published 2001 Journal Mol. Pharmacol. Section Abstract Doc Link 11353815 Disease Relevance 0.09 Pain Relevance 1.00
In dorsal horns (level L3-L5) of animals exhibiting chronic below-level pain CCL2 was co-expressed with transmitters and receptors that are involved in nociceptive processing like calcitonin gene-related peptide (CGRP), Substance-P, vanilloid-receptor-1, and its activated phosphorylated form.
Phosphorylation (phosphorylated) of CGRP in dorsal horns associated with nociception, pain and calcitonin gene-related peptide
2) Confidence 0.54 Published 2008 Journal J. Neurotrauma Section Abstract Doc Link 18338959 Disease Relevance 0.97 Pain Relevance 0.90
In dorsal horns (level L3-L5) of animals exhibiting chronic below-level pain CCL2 was co-expressed with transmitters and receptors that are involved in nociceptive processing like calcitonin gene-related peptide (CGRP), Substance-P, vanilloid-receptor-1, and its activated phosphorylated form.
Phosphorylation (phosphorylated) of calcitonin gene-related peptide in dorsal horns associated with nociception, pain and calcitonin gene-related peptide
3) Confidence 0.54 Published 2008 Journal J. Neurotrauma Section Abstract Doc Link 18338959 Disease Relevance 0.98 Pain Relevance 0.90

General Comments

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