INT95798

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Context Info
Confidence 0.33
First Reported 2001
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.43
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (SORT1) endosome (SORT1) transport (SORT1)
Golgi apparatus (SORT1) endoplasmic reticulum (SORT1) enzyme binding (SORT1)
SORT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 1 63.76 Quite High
tetrodotoxin 1 56.00 Quite High
metalloproteinase 5 5.00 Very Low Very Low Very Low
Serotonin 5 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
fluoxetine 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 12 88.16 High High
Spinal Cord Diseases 1 82.48 Quite High
Colon Cancer 1 78.92 Quite High
Vasculitis 1 67.84 Quite High
Adhesions 9 58.72 Quite High
Shock 1 54.76 Quite High
Pulmonary Hypertension 85 41.16 Quite Low
Aging 1 29.60 Quite Low
Frailty 1 8.36 Low Low
Disease 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sortilin 1 (SORT1) represents a multi-ligand type-1 receptor which binds a number of unrelated ligands that participate in a wide range of cellular processes.
SORT1 Binding (binds) of
1) Confidence 0.33 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1829400 Disease Relevance 0.23 Pain Relevance 0.03
Specific binding of 50 pM (125)I-NT was inhibited by NT(8-13) > NT > SR142948A > or = neuromedin N > or = SR48692, consistent with binding to the NT1 receptor.
NT1 receptor Binding (binding) of
2) Confidence 0.05 Published 2001 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 11356931 Disease Relevance 0.08 Pain Relevance 0.06
This peptide is related to neurotensin and both bind the neurotensin-1 receptor [reviewed in [59]].
neurotensin-1 receptor Binding (bind) of
3) Confidence 0.01 Published 2006 Journal Respir Res Section Body Doc Link PMC1351173 Disease Relevance 0.13 Pain Relevance 0

General Comments

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