INT95801

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Context Info
Confidence 0.43
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ptger1) plasma membrane (Ptger1) signal transducer activity (Ptger1)
Anatomy Link Frequency
afferent neurons 2
Ptger1 (Mus musculus)
Pain Link Frequency Relevance Heat
qutenza 2 99.76 Very High Very High Very High
Deafferentation 2 79.28 Quite High
antagonist 1 65.56 Quite High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Targeted Disruption 4 91.88 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present findings confirmed a role for endogenous PGE2 produced by COX-1 in adaptive gastric cytoprotection and suggested that this action is mediated by activation of EP1-receptors but not associated with capsaicin-sensitive afferent neurons.
Positive_regulation (activation) of EP1 Binding (associated) of in afferent neurons associated with qutenza
1) Confidence 0.43 Published 2001 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 11356942 Disease Relevance 0.25 Pain Relevance 0.28

General Comments

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