INT959

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Context Info
Confidence 0.47
First Reported 1979
Last Reported 2009
Negated 2
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 5.04
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear chromosome (ATRX) nucleus (ATRX) helicase activity (ATRX)
DNA binding (ATRX)
Anatomy Link Frequency
wrist 2
lips 1
ATRX (Homo sapiens)
Pain Link Frequency Relevance Heat
corticosteroid 4 100.00 Very High Very High Very High
Clonidine 2 98.62 Very High Very High Very High
Pain 2 97.14 Very High Very High Very High
Dopamine 4 93.64 High High
Central nervous system 4 90.64 High High
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 79 100.00 Very High Very High Very High
Pressure And Volume Under Development 16 100.00 Very High Very High Very High
Injury 4 100.00 Very High Very High Very High
Lymphedema 2 99.84 Very High Very High Very High
Contracture 20 98.56 Very High Very High Very High
Congenital Anomalies 6 93.88 High High
Arthrogryposis 17 85.64 High High
Stroke 4 75.00 Quite High
Strabismus 1 69.84 Quite High
Scoliosis 2 68.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These drugs did not affect SHS behavior.
Neg (not) Regulation (affect) of SHS
1) Confidence 0.47 Published 1979 Journal Psychopharmacology (Berl.) Section Abstract Doc Link 117484 Disease Relevance 0 Pain Relevance 0.26
Based on systematic analysis of the literature, the following conclusions seem justified: (i) the shoulder is involved in only half of the cases with painful swelling of wrist and hand, suggesting a "wrist-hand syndrome" between simple hand oedema and SHS; (ii) hand oedema is not lymphoedema; (iii) SHS usually coincides with increased arterial blood flow; (iv) trauma causes aseptic joint inflammations in SHS; (v) no specific treatment has yet proven its advantage over other physical methods for reducing hand oedema; and (vi) oral corticosteroids are the most effective treatment for SHS.
Regulation (effective) of SHS in wrist associated with pain, pressure and volume under development, corticosteroid, syndrome, injury and lymphedema
2) Confidence 0.39 Published 2000 Journal Scand J Rehabil Med Section Abstract Doc Link 10782934 Disease Relevance 1.70 Pain Relevance 0.19
Based on systematic analysis of the literature, the following conclusions seem justified: (i) the shoulder is involved in only half of the cases with painful swelling of wrist and hand, suggesting a "wrist-hand syndrome" between simple hand oedema and SHS; (ii) hand oedema is not lymphoedema; (iii) SHS usually coincides with increased arterial blood flow; (iv) trauma causes aseptic joint inflammations in SHS; (v) no specific treatment has yet proven its advantage over other physical methods for reducing hand oedema; and (vi) oral corticosteroids are the most effective treatment for SHS.
Regulation (effective) of SHS in wrist associated with pain, pressure and volume under development, corticosteroid, syndrome, injury and lymphedema
3) Confidence 0.39 Published 2000 Journal Scand J Rehabil Med Section Abstract Doc Link 10782934 Disease Relevance 1.60 Pain Relevance 0.18
Newborns affected with SHS do not have the pinched lips accompanied by the appearance of a "whistling face" nor do they typically have "H" shaped dimpling of the chin.
Regulation (affected) of SHS in lips associated with syndrome
4) Confidence 0.34 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2663550 Disease Relevance 1.73 Pain Relevance 0
Phentolamine, phenoxybenzamine, clonidine, isoproterenol, and propranolol given ICV or systemically showed no effect on either SHS or SG behaviors.
Neg (no) Regulation (effect) of SHS associated with clonidine
5) Confidence 0.18 Published 1979 Journal Psychopharmacology (Berl.) Section Abstract Doc Link 117484 Disease Relevance 0 Pain Relevance 0.27

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