INT95901

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Context Info
Confidence 0.04
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Grip2) plasma membrane (Grip2) cytoskeleton (Grip2)
cytoplasm (Grip2)
Grip2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 3 100.00 Very High Very High Very High
nMDA receptor antagonist 1 96.32 Very High Very High Very High
antagonist 4 94.88 High High
Glutamate 6 85.52 High High
tetrodotoxin 3 82.64 Quite High
nMDA receptor 1 75.00 Quite High
gABA 1 66.72 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Under blockade of AMPA receptors, the kainate- and GluR5-selective kainate receptor agonists, (RS)-2-amino-3-(3-hydroxy-5-tert-butylisoxazol-4-yl) propanoic acid) (ATPA) and (S)-5-iodowillardiine (5IWill), induced a large enhancement of the frequency of small-amplitude sIPSC which was blocked by the non-NMDA receptor antagonist, 2,3-dihydro-6-nitro-7-sulfamoyl-benzo(f)quinoxaline (NBQX).
Positive_regulation (induced) of Negative_regulation (blockade) of AMPA associated with nmda receptor antagonist and agonist
1) Confidence 0.04 Published 2001 Journal Neuropharmacology Section Abstract Doc Link 11369028 Disease Relevance 0 Pain Relevance 0.75

General Comments

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